• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

Human health hazards of veterinary medications: information for emergency departments.

作者信息

Lust Elaine Blythe, Barthold Claudia, Malesker Mark A, Wichman Tammy O

机构信息

Regulatory Affairs, Professional Veterinary Products, Ltd., Omaha, Nebraska, USA.

出版信息

J Emerg Med. 2011 Feb;40(2):198-207. doi: 10.1016/j.jemermed.2009.09.026. Epub 2010 Jan 4.

DOI:10.1016/j.jemermed.2009.09.026
PMID:20045604
Abstract

BACKGROUND

There are over 5000 approved prescription and over-the-counter medications, as well as vaccines, with labeled indications for veterinary patients. Of these, there are several products that have significant human health hazards upon accidental or intentional exposure or ingestion in humans: carfentanil, clenbuterol (Ventipulmin), ketamine, tilmicosin (Micotil), testosterone/estradiol (Component E-H and Synovex H), dinoprost (Lutalyse/Prostamate), and cloprostenol (Estromate/EstroPlan). The hazards range from mild to life-threatening in terms of severity, and include bronchospasm, central nervous system stimulation, induction of miscarriage, and sudden death.

OBJECTIVE

To report medication descriptions, human toxicity information, and medical management for the emergent care of patients who may have had exposure to veterinary medications when they present to an emergency department (ED).

DISCUSSION

The intended use of this article is to inform and support ED personnel, drug information centers, and poison control centers on veterinary medication hazards.

CONCLUSION

There is a need for increased awareness of the potential hazards of veterinary medications within human medicine circles. Timely reporting of veterinary medication hazards and their medical management may help to prepare the human medical community to deal with such exposures or abuses when time is of the essence.

摘要

相似文献

1
Human health hazards of veterinary medications: information for emergency departments.
J Emerg Med. 2011 Feb;40(2):198-207. doi: 10.1016/j.jemermed.2009.09.026. Epub 2010 Jan 4.
2
Methylphenidate poisoning: an evidence-based consensus guideline for out-of-hospital management.哌甲酯中毒:院外管理的循证共识指南
Clin Toxicol (Phila). 2007 Oct-Nov;45(7):737-52. doi: 10.1080/15563650701665175.
3
Atypical antipsychotic medication poisoning: an evidence-based consensus guideline for out-of-hospital management.非典型抗精神病药物中毒:院外管理的循证共识指南
Clin Toxicol (Phila). 2007 Dec;45(8):918-42. doi: 10.1080/15563650701665142.
4
Human exposures to tilmicosin (MICOTIL).人类接触替米考星(迈克替)的情况。
Vet Hum Toxicol. 1994 Aug;36(4):306-8.
5
Analysis of reports of human exposure to Micotil 300 (tilmicosin injection).人类接触 Micotil 300(替米考星注射液)的报告分析。
J Am Vet Med Assoc. 2006 Dec 1;229(11):1737-42. doi: 10.2460/javma.229.11.1737.
6
Salicylate poisoning: an evidence-based consensus guideline for out-of-hospital management.水杨酸盐中毒:院外管理的循证共识指南
Clin Toxicol (Phila). 2007;45(2):95-131. doi: 10.1080/15563650600907140.
7
Tricyclic antidepressant poisoning: an evidence-based consensus guideline for out-of-hospital management.三环类抗抑郁药中毒:院外管理的循证共识指南
Clin Toxicol (Phila). 2007;45(3):203-33. doi: 10.1080/15563650701226192.
8
2012 Annual Report of the American Association of Poison Control Centers' National Poison Data System (NPDS): 30th Annual Report.2012 年美国毒物控制中心协会国家毒物数据系统(NPDS)年度报告:第 30 年度报告。
Clin Toxicol (Phila). 2013 Dec;51(10):949-1229. doi: 10.3109/15563650.2013.863906.
9
Administration of micotil.米考星的给药
Vet Rec. 2009 Sep 19;165(12):355-6. doi: 10.1136/vr.165.12.355.
10
Association between second-generation antipsychotic medication half-life and hospitalization in the community treatment of adult schizophrenia.第二代抗精神病药物半衰期与成人精神分裂症社区治疗住院的相关性。
J Med Econ. 2012;15(1):105-11. doi: 10.3111/13696998.2011.632042. Epub 2011 Oct 28.

引用本文的文献

1
Carfentanil stabilizes µ opioid receptor conformations that are ultra-efficient in inhibiting cAMP, resistant to naloxone or nalmefene but sensitive to naltrexone.卡芬太尼可稳定μ阿片受体构象,这些构象在抑制环磷酸腺苷(cAMP)方面效率极高,对纳洛酮或纳美芬具有抗性,但对纳曲酮敏感。
Arch Toxicol. 2025 May 3. doi: 10.1007/s00204-025-04048-6.
2
Exploring the Confluence of Animal Medicine and its Implications for Human Health: A Systematic Literature Review.探索兽医学的融合及其对人类健康的影响:一项系统文献综述
Curr Neuropharmacol. 2025;23(7):847-861. doi: 10.2174/011570159X333443240822115028.
3
Carfentanil is a β-arrestin-biased agonist at the μ opioid receptor.
卡芬太尼是一种 μ 阿片受体的β-arrestin 偏向激动剂。
Br J Pharmacol. 2023 Sep;180(18):2341-2360. doi: 10.1111/bph.16084. Epub 2023 May 18.
4
New Synthetic Opioids: Clinical Considerations and Dangers.新型合成阿片类药物:临床考量与风险
Pain Ther. 2023 Apr;12(2):399-421. doi: 10.1007/s40122-023-00481-6. Epub 2023 Feb 24.
5
Determination of Nine Fentanyl Drugs in Hair Samples by GC-MS/MS and LC-MS/MS.采用气相色谱-串联质谱法和液相色谱-串联质谱法测定毛发样本中的九种芬太尼类药物。
ACS Omega. 2022 May 31;7(23):19176-19182. doi: 10.1021/acsomega.2c00087. eCollection 2022 Jun 14.
6
Drug Misuse in the Veterinary Setting: an Under-recognized Avenue.兽医环境中的药物滥用:一个被低估的途径。
Curr Psychiatry Rep. 2021 Jan 6;23(2):3. doi: 10.1007/s11920-020-01214-8.
7
Fatalities caused by novel opioids: a review.新型阿片类药物所致死亡:综述
Forensic Sci Res. 2018 May 7;4(2):95-110. doi: 10.1080/20961790.2018.1460063. eCollection 2019.
8
Carfentanil: a narrative review of its pharmacology and public health concerns.卡芬太尼:药理学和公共健康关注点的叙述性综述。
Can J Anaesth. 2019 Apr;66(4):414-421. doi: 10.1007/s12630-019-01294-y. Epub 2019 Jan 21.
9
Calculate of withdrawal times of clenbuterol in goats to obtain safe times of slaughter.计算山羊中盐酸克伦特罗的停药时间以获得安全屠宰时间。
Vet World. 2018 Jun;11(6):731-738. doi: 10.14202/vetworld.2018.731-738. Epub 2018 Jun 1.
10
Recruitment to doping and help-seeking behavior of eight female AAS users.八名女性合成代谢类固醇使用者的兴奋剂使用招募情况及求助行为
Subst Abuse Treat Prev Policy. 2016 Mar 5;11:11. doi: 10.1186/s13011-016-0056-3.