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八名女性合成代谢类固醇使用者的兴奋剂使用招募情况及求助行为

Recruitment to doping and help-seeking behavior of eight female AAS users.

作者信息

Börjesson Annica, Gårevik Nina, Dahl Marja-Liisa, Rane Anders, Ekström Lena

机构信息

Department of Laboratory Medicine, Karolinska Institutet, Karolinska University Hospital, SE-141 86, Stockholm, Sweden.

Department of Clinical Pharmacology, Karolinska University Hospital, SE-141 86, Stockholm, Sweden.

出版信息

Subst Abuse Treat Prev Policy. 2016 Mar 5;11:11. doi: 10.1186/s13011-016-0056-3.

Abstract

BACKGROUND

Doping with anabolic androgenic steroids in sports has now developed to a widespread use of these agents among young people outside the sport. This is of major concern to the society. The purpose of the use is mainly for aesthetic reasons and is seen as a male phenomenon. But use also occurs in women where the knowledge is scarce. Our aim was to identify the pattern of doping agents in eight female cases and compare them with similar data from men.

METHODS

Eight female users were recruited through Anti-Doping Hot-Line, a national telephone counseling service on doping issues during the years 1998-2004. The use was confirmed with urine doping analysis at the Doping Laboratory. The characteristic of use, co-use of narcotics/other doping agents, exercise pattern, adverse-side effects, family history and reason to begin was evaluated.

RESULTS

The women used on average 1.9 different anabolic androgenic steroids and clenbuterol preparations. Ephedrine and growth hormone were co-used in five and one of the women, respectively. Three women reported co-use of narcotics (cannabis and cocaine). The average duration of anabolic agent use before contacting health care was 58 weeks (range 7-104). Side effects for anabolic androgenic steroids (n = 5) included voice changes, clitoral enlargement, body hair growth, whereas women using clenbuterol (n = 2) reported tachycardia and depression. All women except one had a man in close relationship encouraging them to begin with the doping agents.

CONCLUSIONS

The use of doping agents in our eight women was different from that in male users. The women used less doping agents and were more prone to contact the health care, at an earlier stage, probably due to the adverse effects. The co-use with ephedrine, growth hormone and cannabis appeared to be in the same range as in men. This is the first study showing that a man in close relationship may motivate a woman to use anabolic agents.

摘要

背景

在体育运动中使用合成代谢雄激素类固醇如今已发展为这些药物在体育界之外的年轻人中广泛使用。这引起了社会的重大关注。使用这些药物的目的主要是出于审美原因,且被视为男性现象。但女性中也存在使用情况,而这方面的认知较为匮乏。我们的目的是确定八名女性使用者的 doping 药物模式,并将其与男性的类似数据进行比较。

方法

通过反兴奋剂热线招募了八名女性使用者,该热线是 1998 年至 2004 年期间关于 doping 问题的国家电话咨询服务。在兴奋剂检测实验室通过尿液 doping 分析确认了使用情况。评估了使用特征、与麻醉药品/其他 doping 药物的联合使用、锻炼模式、不良反应、家族史以及开始使用的原因。

结果

这些女性平均使用 1.9 种不同的合成代谢雄激素类固醇和克仑特罗制剂。分别有五名和一名女性同时使用麻黄碱和生长激素。三名女性报告同时使用麻醉药品(大麻和可卡因)。在联系医疗保健之前,合成代谢药物的平均使用时长为 58 周(范围 7 - 104 周)。合成代谢雄激素类固醇(n = 5)的副作用包括声音变化、阴蒂增大、体毛生长,而使用克仑特罗的女性(n = 2)报告有心悸和抑郁。除一名女性外,所有女性都有亲密关系的男性鼓励她们开始使用 doping 药物。

结论

我们研究的八名女性使用 doping 药物的情况与男性使用者不同。女性使用的 doping 药物较少,并且可能由于不良反应,在更早阶段更倾向于联系医疗保健。与麻黄碱、生长激素和大麻的联合使用情况似乎与男性处于同一范围。这是第一项表明亲密关系中的男性可能促使女性使用合成代谢药物的研究。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/75c1/4779574/23bab3a82d98/13011_2016_56_Fig1_HTML.jpg

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