母体维生素D缺乏所致的先天性佝偻病。
Congenital rickets caused by maternal vitamin D deficiency.
作者信息
Innes A Micheil, Seshia Molly M, Prasad Chitra, Al Saif Saif, Friesen Frank R, Chudley Albert E, Reed Martin, Dilling Louise A, Haworth James C, Greenberg Cheryl R
机构信息
Departments of Pediatrics and Child Health.
出版信息
Paediatr Child Health. 2002 Sep;7(7):455-8. doi: 10.1093/pch/7.7.455.
Abstract
The cases of four newborn infants with congenital rickets are reported. All infants were native Canadian: three were Cree and one was Inuit. One had a narrow chest and pulmonary hypoplasia, two had clinical and radiological signs of rickets with craniotabes, thickened wrists, and prominent costochondral junctions, and one had perinatal asphyxia and hydrops. All had hypocalcemia, hypophosphatemia and secondary hyperparathyroidism. Serum 25-hydroxyvitamin D levels were low in three of the infants. The four mothers had evidence of vitamin D deficiency. All infants recovered following treatment with 5000 IU oral vitamin D daily.
摘要
报告了4例先天性佝偻病新生儿病例。所有婴儿均为加拿大原住民：3例是克里族，1例是因纽特族。1例有胸廓狭窄和肺发育不全，2例有佝偻病的临床和放射学体征，如颅骨软化、手腕增粗和肋软骨连接处突出，1例有围产期窒息和水肿。所有患儿均有低钙血症、低磷血症和继发性甲状旁腺功能亢进。3例婴儿血清25-羟维生素D水平较低。4位母亲均有维生素D缺乏的证据。所有婴儿每日口服5000 IU维生素D治疗后均康复。
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本文引用的文献
1
Lesson of the week: florid rickets associated with prolonged breast feeding without vitamin D supplementation.
BMJ. 1999 Jan 2;318(7175):39-40. doi: 10.1136/bmj.318.7175.39.
2
[Nutritional fetal rickets. A case report].
J Gynecol Obstet Biol Reprod (Paris). 1997;26(8):834-6.
3
Vitamin D deficiency in a Manitoba community.
Can J Public Health. 1993 Nov-Dec;84(6):394-6.
4
Observations on the vitamin D state of pregnant Asian women in London.
Br J Obstet Gynaecol. 1981 Jan;88(1):18-26. doi: 10.1111/j.1471-0528.1981.tb00931.x.
5
Congenital hyperparathyroidism and rickets: secondary to maternal hypoparathyroidism and vitamin D deficiency.
Isr J Med Sci. 1981 Aug;17(8):705-8.
6
Congenital rickets -- a case report.
Aust Paediatr J. 1982 Dec;18(4):291-3.
7
Annual high-dose vitamin D prophylaxis in Asian immigrants.
Lancet. 1981 Nov 28;2(8257):1199-202. doi: 10.1016/s0140-6736(81)91439-2.
8
Neonatal rickets in Asian immigrant population.
Br Med J. 1973 Jul 28;3(5873):211-2. doi: 10.1136/bmj.3.5873.211.
9
Congenital rickets due to maternal vitamin D deficiency.
Arch Dis Child. 1974 Oct;49(10):810-1. doi: 10.1136/adc.49.10.810.
10
Pathogenesis of hereditary vitamin-D-dependent rickets. An inborn error of vitamin D metabolism involving defective conversion of 25-hydroxyvitamin D to 1 alpha,25-dihydroxyvitamin D.
N Engl J Med. 1973 Oct 18;289(16):817-22. doi: 10.1056/NEJM197310182891601.
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