Blond M H, Gold F, Pierre F, Berger C, Guerois M, Queru M S, Ramponi N
Service de Médecine Néonatale, Centre de Pédiatrie Gatien de Clocheville, Tours.
J Gynecol Obstet Biol Reprod (Paris). 1997;26(8):834-6.
We report the case of a newborn who showed typical signs of rickets at birth craniotabes and severe hypocalcemia. The diagnosis of fetal rickets was confirmed by radiography. Maternal deficiency was revealed by an excessively low vitamin D level. The multiparous Moroccan mother had suffered low back pain and paraesthesia for several years. She wore the veil and rarely left her home. Nutritional and vitamin D deficiency was demonstrated. We report this exceptional case to recall the importance of vitamin D in the development of fetal calcium supply, the prevention of gravid osteomalacia and the prevention of neonatal hypocalcemia. Vitamin D supplementation (ideally 1000 IU per day during the third trimester or at least one 100,000 IU dose at the sixth and eighth months or a single dose of 2 to 3,000,000 IU at the sixth month) should be the rule in pregnancy.
我们报告了一例新生儿病例，该新生儿出生时即表现出佝偻病的典型症状——颅骨软化和严重低钙血症。通过X线检查确诊为胎儿佝偻病。母亲维生素D水平过低揭示了母体缺乏。这位多次生育的摩洛哥母亲多年来一直遭受腰痛和感觉异常。她戴着面纱，很少出门。证实存在营养和维生素D缺乏。我们报告这一特殊病例，以提醒人们维生素D在胎儿钙供应发育、预防妊娠性骨软化症以及预防新生儿低钙血症中的重要性。孕期应常规补充维生素D（理想情况下，孕晚期每天补充1000国际单位，或在第六和第八个月至少补充一剂100,000国际单位，或在第六个月单次补充2至3,000,000国际单位）。
