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韩国抑郁障碍患者的述情障碍与应激反应模式。

Alexithymia and Stress Response Patterns among Patients with Depressive Disorders in Korea.

机构信息

Department of Psychiatry, School of Medicine, Kyungpook National University, Daegu, Korea.

出版信息

Psychiatry Investig. 2009 Mar;6(1):13-8. doi: 10.4306/pi.2009.6.1.13. Epub 2009 Mar 31.

Abstract

OBJECTIVE

Alexithymic characteristics may represent cognitive and affective mediators between stressors and stress responses among those with depressive disorders. This study evaluated how alexithymic characteristics, as measured by the Korean version of the Toronto Alexithymia Scale-20 (TAS-20K), could be related to stress response patterns, as measured by the Stress Response Inventory (SRI), within a sample composed of individuals diagnosed with depressive disorders.

METHODS

Participants comprised a cross section of patients diagnosed with depressive disorders (n=98). Data on demographic and psychosocial factors (i.e., sex, age, and level of education), clinical profiles {i.e., primary and comorbid psychiatric conditions meeting the Diagnostic and Statistical Manual of Mental Disorders, fourth edition (DSM-IV) criteria at the time of the evaluation}, duration of illness, medications, and Clinical Global Impression (CGI) scores, and the results of psychological assessments (TAS-20K, SRI) were analyzed.

RESULTS

Patients having depressive disorders with alexithymia obtained significantly higher scores in terms of all seven subscales of the SRI, as compared to those without alexithymia, a logistic regression model was used to assess possible predictors for the presence of alexithymia in patients with depressive disorders, including the seven subscales of the SRI, gender, age, and duration of illness. We found that aggressive and somatizing responses to stress were significantly associated with the presence of alexithymia among patients with depression.

CONCLUSION

These findings suggest that patients having depression with alexithymia were more susceptible to stress than those without alexithymia. Clinicians might improve their treatment of depression by identifying the clinical predictors for alexithymia and by helping those individuals demonstrating such symptoms in coping with emotionally stressful situations.

摘要

目的

述情障碍特征可能代表抑郁障碍患者应激源和应激反应之间的认知和情感中介。本研究评估了用 20 项多伦多述情障碍量表-韩国版(TAS-20K)测量的述情障碍特征如何与应激反应模式相关,应激反应模式用应激反应量表(SRI)测量,研究对象为被诊断为抑郁障碍的个体。

方法

参与者为一组被诊断为抑郁障碍的患者(n=98)。数据包括人口统计学和社会心理因素(即性别、年龄和受教育程度)、临床特征(即在评估时符合《精神障碍诊断与统计手册》第四版(DSM-IV)标准的原发性和共病精神疾病)、疾病持续时间、药物治疗和临床总体印象(CGI)评分,以及心理评估(TAS-20K、SRI)的结果。

结果

与无述情障碍的患者相比,患有抑郁障碍且存在述情障碍的患者在 SRI 的所有七个分量表上的得分明显更高,采用逻辑回归模型评估了可能预测抑郁障碍患者存在述情障碍的因素,包括 SRI 的七个分量表、性别、年龄和疾病持续时间。我们发现,对压力的攻击和躯体化反应与抑郁患者存在述情障碍显著相关。

结论

这些发现表明,患有抑郁障碍且存在述情障碍的患者比无述情障碍的患者更容易受到压力的影响。临床医生可以通过识别述情障碍的临床预测因素,并帮助那些表现出这种症状的人应对情绪压力,从而改善他们对抑郁的治疗。

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