溶血性尿毒症综合征：过去十年的事件
Hemolytic uremic syndrome: Events of the past decade.
作者信息
McLaine Peter N
机构信息
Department of Pediatrics, University of Ottawa; Children's Hospital of Eastern Ontario; Canadian Pediatric Kidney Disease Research Centre, Ottawa, Ontario.
出版信息
Paediatr Child Health. 2002 Oct;7(8):533-7. doi: 10.1093/pch/7.8.533.
This article describes the birth of the Canadian Pediatric Kidney Disease Research Centre (CPKDRC) in 1985 and the activities that have transpired as a result of collaborative research at paediatric centres across Canada. These include the National Retrospective Study of Childhood Hemolytic Uremic Syndrome (HUS), National Prospective Study of Risk Factors for Developing Escherichia coli O157:H7 Infection, and Intervention Studies for the Prevention of HUS. A look to the future describes possible studies to determine potential factors (surrogate markers) to identify children who are at risk for developing HUS following verotoxin-producing E coli gastroenteritis, other intervention studies and a more accurate understanding of permanent renal insufficiency in children who have had HUS.
本文介绍了加拿大儿童肾病研究中心（CPKDRC）于1985年的成立，以及加拿大各儿科中心合作研究所开展的活动。这些活动包括全国儿童溶血尿毒综合征（HUS）回顾性研究、大肠杆菌O157:H7感染危险因素全国前瞻性研究以及HUS预防干预研究。展望未来，将描述可能开展的研究，以确定潜在因素（替代标志物），从而识别在产志贺毒素大肠杆菌性肠胃炎后有患HUS风险的儿童，其他干预研究，以及更准确地了解患过HUS的儿童的永久性肾功能不全情况。
Zotero 插件