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上睑外毛根鞘癌：一例报告

Trichilemmal carcinoma of the upper eyelid: a case report.

作者信息

Lee Ju Hyang, Shin Yong Woon, Oh Young Ha, Lee Yoon Jung

机构信息

Department of Ophthalmology, Hanyang University School of Medicine, Seoul, Korea.

出版信息

Korean J Ophthalmol. 2009 Dec;23(4):301-5. doi: 10.3341/kjo.2009.23.4.301. Epub 2009 Dec 4.

DOI:10.3341/kjo.2009.23.4.301
PMID:20046693
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2789957/
Abstract

We report a very rare case of trichilemmal carcinoma (TLC) involving the upper eyelid. To the best of our knowledge, this is the first report of trichilemmal carcinoma of the upper eyelid in Korea. A 51-year-old man presented to our hospital complaining of a bloody discharge from his left upper eyelid. He had a soft and lobulated mass on the palpebral conjunctiva. An incisional biopsy revealed trabecular growth of tumor cells with clear cytoplasm, prominent nucleoli, frequent mitoses, and foci of trichilemmal keratinization. Immunohistochemically, the lesion was positive for p53 and negative for CD 34. A diagnosis of TLC was made, and total excision of the mass and reconstruction of the eyelid were performed. Trichilemmal carcinoma is a rare malignant tumor, though it appears to be an indolent neoplasm with no metastatic potential. The treatment of choice for trichilemmal carcinoma of the eyelid is complete excision with tumor-free margins due to the locally invasive nature of the lesion.

摘要

我们报告了一例非常罕见的发生于上睑的毛发上皮癌（TLC）。据我们所知，这是韩国首例关于上睑毛发上皮癌的报告。一名51岁男性因左上睑血性分泌物就诊于我院。他的睑结膜有一个柔软的分叶状肿物。切开活检显示肿瘤细胞呈小梁状生长，胞质透明，核仁明显，有频繁的有丝分裂以及毛发上皮角化灶。免疫组化显示，该病变p53阳性，CD 34阴性。诊断为毛发上皮癌，并对肿物进行了完整切除及眼睑重建。毛发上皮癌是一种罕见的恶性肿瘤，尽管它似乎是一种无转移潜能的惰性肿瘤。由于该病变具有局部浸润性，眼睑毛发上皮癌的首选治疗方法是切缘无肿瘤的完整切除。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b5d8/2789957/369bdca226cd/kjo-23-301-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b5d8/2789957/d45ca400cd79/kjo-23-301-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b5d8/2789957/bc928c0770f9/kjo-23-301-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b5d8/2789957/53924c71deb1/kjo-23-301-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b5d8/2789957/181951cee21c/kjo-23-301-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b5d8/2789957/369bdca226cd/kjo-23-301-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b5d8/2789957/d45ca400cd79/kjo-23-301-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b5d8/2789957/bc928c0770f9/kjo-23-301-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b5d8/2789957/53924c71deb1/kjo-23-301-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b5d8/2789957/181951cee21c/kjo-23-301-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b5d8/2789957/369bdca226cd/kjo-23-301-g005.jpg

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