Drance S M, Douglas G R, Wijsman K J, Schulzer M
Department of Ophthalmology, University of British Columbia, Vancouver, Canada.
Graefes Arch Clin Exp Ophthalmol. 1991;229(1):50-1. doi: 10.1007/BF00172260.
We compared the pressure-lowering effects of timolol, pindolol, epinephrine and the mixture of timolol and epinephrine with that of placebo over a 12-h period. All agents reduced the pressure significantly but with varying time courses. The mixture of timolol and epinephrine reduced the pressure significantly more than did timolol or epinephrine alone, especially at 12 h after the last administration of the drops.
