Ohrström A, Kättström O
Br J Ophthalmol. 1981 Jan;65(1):53-5. doi: 10.1136/bjo.65.1.53.
In a prospective double-blind randomised trial the interaction of timolol and adrenaline was studied in 20 patients with open-angle glaucoma and exfoliative glaucoma. After pretreatment for at least 2 weeks with timolol eyedrops adrenaline was added in a double-blind manner, and the intraocular pressure was recorded during 4 days. The study showed a significantly additive hypotensive effect of adrenaline, which was more pronounced in patients with exfoliative glaucoma.
在一项前瞻性双盲随机试验中,对20例开角型青光眼和剥脱性青光眼患者研究了噻吗洛尔与肾上腺素的相互作用。在用噻吗洛尔滴眼液预处理至少2周后,以双盲方式加入肾上腺素,并在4天内记录眼压。研究显示肾上腺素具有显著的相加性降压作用,在剥脱性青光眼患者中更为明显。