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牛抗缪勒氏管激素和骨连接蛋白基因的体细胞图谱:一个新的牛同线群的鉴定

Somatic cell mapping of the genes for anti-müllerian hormone and osteonectin in cattle: identification of a new bovine syntenic group.

作者信息

Rogers D S, Gallagher D S, Womack J E

机构信息

Department of Veterinary Pathology, Texas A&M University, College Station 77843.

出版信息

Genomics. 1991 Feb;9(2):298-300. doi: 10.1016/0888-7543(91)90256-e.

Abstract

DNA probes from the bovine anti-Müllerian hormone and osteonectin genes were hybridized onto Southern blots containing DNAs from cow-hamster and cow-mouse hybrid somatic cell lines segregating bovine chromosomes. Bovine anti-Müllerian hormone and osteonectin loci were fully concordant with each other in 96 hybrid somatic cell lines, but were not concordant with any other bovine syntenic group described to date. As such, these two genes represent another syntenic group in cattle, bringing to 27 the number of autosomal syntenic groups identified thus far.

摘要

来自牛抗缪勒氏管激素和骨连接蛋白基因的DNA探针与含有牛-仓鼠和牛-小鼠杂种体细胞系DNA的Southern印迹杂交,这些杂种体细胞系正在分离牛染色体。在96个杂种体细胞系中,牛抗缪勒氏管激素和骨连接蛋白基因座彼此完全一致,但与迄今为止描述的任何其他牛同线群不一致。因此,这两个基因代表了牛中的另一个同线群,使迄今确定的常染色体同线群数量增加到27个。

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