The Hospital for Sick Children, Toronto, Canada.
Eur J Pain. 2010 Aug;14(7):735-41. doi: 10.1016/j.ejpain.2009.11.016. Epub 2010 Jan 4.
To describe how (i) risk of neurological impairment (NI) and (ii) procedure invasiveness influence health professionals' assessment and management of procedural pain in neonates in the Neonatal Intensive Care Unit (NICU).
Prospective observational study.
Three tertiary level NICUs in Canada.
114 neonates, 25-40 weeks gestational age (GA) undergoing painful procedures.
Physical and behavioural pain indicators and pharmacological and nonpharmacological pain interventions.
114 neonates at high (Cohort A, n=35), moderate (Cohort B, n=25) and low (Cohort C, n=54) risk of NI were observed during 254 painful procedures performed by 147 health professionals. Physical pain indicators were used more frequently by health professionals to assess pain with Cohorts A and B than C (p<.05). Behavioural pain indicators were used similarly across Cohorts. Nonpharmacological interventions were implemented most frequently for pain management. Physical interventions were used with 84% of procedures across Cohorts; particularly for the most invasive procedures. Infants with the highest NI risk (Cohort A) received the most behavioural interventions (p<.05) irrespective of procedural invasiveness. Pharmacological interventions were implemented with 23.2% of procedures; Cohort B received pharmacological interventions most frequently (Cohort B>A, B>C, p<.05) and for increasingly invasive procedures (p<.05).
Health professionals use multidimensional indicators to assess neonatal pain. Nonpharmacological interventions dominate pain management. NI risk status and procedure invasiveness are important contextual factors in neonatal pain assessment and management.
描述(i)神经损伤风险和(ii)操作侵入性如何影响新生儿重症监护病房(NICU)中医疗保健专业人员对新生儿操作性疼痛的评估和管理。
前瞻性观察研究。
加拿大三个三级 NICU。
114 名胎龄为 25-40 周的患有疼痛性疾病的新生儿。
身体和行为疼痛指标以及药物和非药物疼痛干预措施。
在对 147 名医疗保健专业人员进行的 254 次疼痛操作中,观察到 114 名处于高(队列 A,n=35)、中(队列 B,n=25)和低(队列 C,n=54)神经损伤风险的新生儿。与队列 C 相比,队列 A 和 B 的医疗保健专业人员更频繁地使用身体疼痛指标来评估疼痛(p<.05)。行为疼痛指标在各队列中使用情况相似。非药物干预措施是最常用的疼痛管理方法。物理干预措施在所有队列中均有 84%的操作中使用;尤其是对于最具侵入性的操作。神经损伤风险最高的婴儿(队列 A)接受了最多的行为干预(p<.05),而不论操作的侵入性如何。药物干预措施在 23.2%的操作中实施;队列 B 最常接受药物干预(队列 B>A、B>C,p<.05),并且随着操作侵入性的增加(p<.05)。
医疗保健专业人员使用多维指标来评估新生儿疼痛。非药物干预措施主导疼痛管理。神经损伤风险状况和操作侵入性是新生儿疼痛评估和管理的重要背景因素。