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急性肠系膜上动脉闭塞的流行病学和预后因素。

Epidemiology and prognostic factors in acute superior mesenteric artery occlusion.

机构信息

Vascular Center, Malmö University Hospital, Lund University, Lund, Sweden.

出版信息

J Gastrointest Surg. 2010 Apr;14(4):628-35. doi: 10.1007/s11605-009-1130-1. Epub 2010 Jan 5.

Abstract

BACKGROUND

Reports on trends in incidence and mortality of acute superior mesenteric artery (SMA) occlusion and evaluation of prognostic factors in recent years are lacking.

METHODS

Patients with acute SMA occlusion were identified through the in-patient and autopsy registry between 1970 and 1982 (n = 270), 1987 to 1996 (n = 135), and 2000 and 2006 (n = 100) in Malmö, Sweden.

RESULTS

The overall incidence rate decreased from 8.6 to 5.4/100,000 person years and the autopsy rate from 87% to 25% over time. A higher serum creatinine level was associated with a lower probability of undergoing multi-detector row computed tomography with intravenous contrast (MDCTiv) (p = 0.006). Not performing a MDCTiv (odds ratio 4.0; 95% confidence interval [1.0-16.0]) remained as independent prognostic factor for in-hospital mortality. General and vascular surgeons collaborated in 25 out of 61 patients that underwent an intervention, of which 21 (84%) (p < 0.001) survived.

CONCLUSIONS

A close collaboration between radiologists and general and vascular surgeons seems to be most important to lower the mortality in patients with acute SMA occlusion.

摘要

背景

近年来,关于急性肠系膜上动脉(SMA)闭塞发病率和死亡率趋势的报告以及预后因素的评估较为缺乏。

方法

通过 1970 年至 1982 年(n = 270)、1987 年至 1996 年(n = 135)和 2000 年至 2006 年(n = 100)在瑞典马尔默的住院和尸检登记处,鉴定出急性 SMA 闭塞患者。

结果

总发病率从 8.6/100,000 人年降至 5.4/100,000 人年,尸检率从 87%降至 25%。较高的血清肌酐水平与进行多排螺旋 CT 静脉造影(MDCTiv)的可能性降低相关(p = 0.006)。未进行 MDCTiv(比值比 4.0;95%置信区间 [1.0-16.0])仍然是住院死亡率的独立预后因素。25 例接受介入治疗的患者中有 21 例(84%)(p < 0.001)存活,其中 61 例患者由普外科医生和血管外科医生共同进行治疗。

结论

放射科医生与普外科医生和血管外科医生的密切合作似乎对降低急性 SMA 闭塞患者的死亡率最为重要。

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