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腹主动脉瘤破裂开放修复和血管腔内修复术后预后的预测因素。

Predictors for outcome after open and endovascular repair of ruptured abdominal aortic aneurysms.

作者信息

Acosta S, Lindblad B, Zdanowski Z

机构信息

Department of Vascular Diseases, Malmö University Hospital, Sweden.

出版信息

Eur J Vasc Endovasc Surg. 2007 Mar;33(3):277-84. doi: 10.1016/j.ejvs.2006.09.017. Epub 2006 Nov 9.

DOI:10.1016/j.ejvs.2006.09.017
PMID:17097899
Abstract

OBJECTIVES

The aims of the present study were to analyze patient- and management-related predictors for outcome after open (OR) and endovascular repair (EVAR) of ruptured abdominal aortic aneurysm (rAAA).

DESIGN

Retrospective study.

MATERIALS

The in-hospital registry of Malmö University Hospital identified 162 patients operated on due to rAAA between 2000 and 2004.

METHODS

Patient- and management-related predictors for outcome were analysed.

RESULTS

Preoperative CT in 39 out of 62 circulatory unstable patients was not associated with increased mortality (p=0.60). There was a significant increase in repairs performed by EVAR during the study period (p<0.001), and in 2004 EVAR exceeded the annual rate of OR. Patients in the EVAR group were older (p=0.025), whereas patients in the OR group more often suffered from unconsciousness after presentation (p=0.004). Age, unconsciousness after presentation and haemoglobin were significantly associated with in-hospital mortality when tested in a multivariate logistic regression model (p=0.002, p=0.003 and p<0.001, respectively). The in-hospital mortality for patients undergoing OR and EVAR was 45% (48/106) and 34% (19/56), respectively (p=0.16). Diagnosis of abdominal compartment syndrome (p=0.005) and intestinal infarction (p=0.002) was associated with poor survival.

CONCLUSIONS

Patient-related factors such as age, loss of consciousness and haemoglobin predicts outcome in a population where both emergency OR and EVAR for the treatment of rAAA is feasible.

摘要

目的

本研究旨在分析破裂腹主动脉瘤(rAAA)开放修复术(OR)和血管腔内修复术(EVAR)后与患者及治疗管理相关的预后预测因素。

设计

回顾性研究。

材料

马尔默大学医院的院内登记资料确定了2000年至2004年间因rAAA接受手术的162例患者。

方法

分析与患者及治疗管理相关的预后预测因素。

结果

62例循环不稳定患者中,39例术前CT检查与死亡率增加无关(p = 0.60)。研究期间,EVAR手术量显著增加(p < 0.001),2004年EVAR的年手术率超过了OR。EVAR组患者年龄较大(p = 0.025),而OR组患者就诊后更常出现意识不清(p = 0.004)。在多因素逻辑回归模型中进行检验时,年龄、就诊后意识不清和血红蛋白与院内死亡率显著相关(分别为p = 0.002、p = 0.003和p < 0.001)。接受OR和EVAR治疗的患者院内死亡率分别为45%(48/106)和34%(19/56)(p = 0.16)。腹腔间隔室综合征(p = 0.005)和肠梗死(p = 0.002)的诊断与生存率低相关。

结论

在rAAA的急诊OR和EVAR治疗均可行的人群中,年龄、意识丧失和血红蛋白等患者相关因素可预测预后。

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