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本文引用的文献

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Multimodal pain management after total hip and knee arthroplasty at the Ranawat Orthopaedic Center.拉纳瓦特骨科中心全髋关节和膝关节置换术后的多模式疼痛管理。
Clin Orthop Relat Res. 2009 Jun;467(6):1418-23. doi: 10.1007/s11999-009-0728-7. Epub 2009 Feb 13.
2
Local anesthetics as antimicrobial agents: a review.局部麻醉药作为抗菌剂:综述
Surg Infect (Larchmt). 2008 Apr;9(2):205-13. doi: 10.1089/sur.2007.036.
3
Serum and wound drain ropivacaine concentrations after wound infiltration in joint arthroplasty.关节置换术中伤口浸润后血清及伤口引流液中罗哌卡因的浓度
J Arthroplasty. 2007 Sep;22(6):884-92. doi: 10.1016/j.arth.2006.09.004. Epub 2007 Jul 25.
4
Comparison of peri- and intraarticular analgesia with femoral nerve block after total knee arthroplasty: a randomized clinical trial.全膝关节置换术后关节周围和关节内镇痛与股神经阻滞的比较:一项随机临床试验
Acta Orthop. 2007 Apr;78(2):172-9. doi: 10.1080/17453670710013645.
5
Efficacy of periarticular multimodal drug injection in total knee arthroplasty. A randomized trial.关节周围多模式药物注射在全膝关节置换术中的疗效:一项随机试验
J Bone Joint Surg Am. 2006 May;88(5):959-63. doi: 10.2106/JBJS.E.00344.
6
A multimodal analgesia protocol for total knee arthroplasty. A randomized, controlled study.全膝关节置换术的多模式镇痛方案。一项随机对照研究。
J Bone Joint Surg Am. 2006 Feb;88(2):282-9. doi: 10.2106/JBJS.E.00173.
7
Continuous intra-articular infusion of bupivacaine for postoperative pain following total knee arthroplasty.布比卡因持续关节腔内输注用于全膝关节置换术后疼痛
J Knee Surg. 2005 Jul;18(3):197-202. doi: 10.1055/s-0030-1248181.
8
Accelerated rehabilitation after total knee replacement.全膝关节置换术后的加速康复
Knee. 2005 Oct;12(5):346-50. doi: 10.1016/j.knee.2004.11.007.
9
Increased flexion and reduced hospital stay with continuous intraarticular morphine and ropivacaine after primary total knee replacement: open intervention study of efficacy and safety in 154 patients.初次全膝关节置换术后持续关节腔内注射吗啡和罗哌卡因可增加膝关节屈曲度并缩短住院时间:154例患者的疗效与安全性开放性干预研究
Acta Orthop Scand. 2004 Oct;75(5):606-9. doi: 10.1080/00016470410001501.
10
The use of the pain pump and patient-controlled analgesia in joint reconstruction.疼痛泵及患者自控镇痛在关节重建中的应用。
Am J Orthop (Belle Mead NJ). 2004 May;33(5 Suppl):10-2.

全膝关节置换术后镇痛:罗哌卡因关节内持续输注。

Postoperative analgesia in TKA: ropivacaine continuous intraarticular infusion.

机构信息

Knee Division, Department of Orthopedics, La Paz University Hospital, Madrid, Spain.

出版信息

Clin Orthop Relat Res. 2010 May;468(5):1242-7. doi: 10.1007/s11999-009-1202-2.

DOI:10.1007/s11999-009-1202-2
PMID:20049572
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2853675/
Abstract

BACKGROUND

Postoperative pain control is a challenge in patients undergoing TKA due to side effects and technical limitations of current analgesic approaches. Local anesthetic infiltration through continuous infusion pumps has been shown to reduce postoperative pain in previous studies.

QUESTIONS/PURPOSES: We assessed the effectiveness of intraarticular ropivacaine infusions in reducing pain and postoperative opioid use after TKA and determined whether such infusions accelerate functional recovery of the patient and reduce length of hospital stay.

METHODS

In a randomized, prospective, double-blind study, two groups were assigned: Group A (n = 25) underwent continuous intraarticular infusion with 300 mL ropivacaine 0.2% at a speed of 5 mL/hour through an elastomeric infusion pump and Group B (n = 25) had an elastomeric pump insertion with 300 mL saline solution at an infusion speed of 5 mL/hour. All patients had the same prosthesis model implanted. Parameters analyzed over the first 3 days, at discharge, and 1 month later included postoperative pain, joint function, opioid use, and length of hospital stay.

RESULTS

All patients in Group A showed a decrease in pain intensity measured by a visual analog scale and opioid use in the first 3 days. Mean length of hospital stay was also reduced in Group A (5.72 days) compared to Group B (7.32 days). There were no device-related complications.

CONCLUSIONS

Use of an infusion pump is effective in treating pain after TKA, reducing postoperative pain and opioid use. It also improves immediate functionality and patient comfort, reducing the mean length of hospital stay, without increasing the risk of complications.

LEVEL OF EVIDENCE

Level I, therapeutic study. See Guidelines for Authors for a complete description of levels of evidence.

摘要

背景

由于当前镇痛方法的副作用和技术限制,接受 TKA 的患者术后疼痛控制是一个挑战。先前的研究表明,通过连续输注泵进行局部麻醉浸润可以减轻术后疼痛。

问题/目的:我们评估了关节内罗哌卡因输注在减少 TKA 后疼痛和术后阿片类药物使用的有效性,并确定这种输注是否能加速患者的功能恢复并减少住院时间。

方法

在一项随机、前瞻性、双盲研究中,将两组患者进行分组:A 组(n = 25)通过弹性输注泵以 5 毫升/小时的速度持续输注 300 毫升 0.2%罗哌卡因;B 组(n = 25)以相同的输注速度通过弹性输注泵输注 300 毫升生理盐水。所有患者均植入相同的假体模型。在术后第 1、3 天、出院时和 1 个月后分析的参数包括术后疼痛、关节功能、阿片类药物使用和住院时间。

结果

A 组所有患者在术后第 1、3 天内疼痛强度和阿片类药物使用均降低。A 组的平均住院时间也比 B 组(7.32 天)短(5.72 天)。未发生与设备相关的并发症。

结论

使用输注泵治疗 TKA 后疼痛有效,可减少术后疼痛和阿片类药物使用。它还可以改善即时功能和患者舒适度,缩短平均住院时间,而不会增加并发症的风险。

证据水平

I 级,治疗研究。有关证据水平的完整描述,请参见作者指南。