Andrade Marta M, Barros Maria Teresa
REQUIMTE, CQFB, Departamento de Quimica, Faculdade de Ciencias e Tecnologia, Universidade Nova de Lisboa, 2829-516 Caparica, Portugal.
J Comb Chem. 2010 Mar 8;12(2):245-7. doi: 10.1021/cc9001444.
A variety of N-acylhydrazones were synthesized under microwave irradiation within 2.5-10 min, starting from benzo, salicyloyl, and isonicotinic hydrazides. The protocol developed employs microwave irradiation in the absence of solvents and catalysts, leading to high yields. The results are reproducible in a 500 mg to 5 g scale.
以苯甲酰肼、水杨酰肼和异烟酰肼为原料，在微波辐射下2.5 - 10分钟内合成了多种N - 酰腙。所开发的方法在无溶剂和催化剂的情况下采用微波辐射，产率很高。该结果在500毫克至5克规模下可重现。
