Lee Candace Y W, Ratnapalan Savithiri, Thompson Margaret, Nathan Paul C, Closs Jordan, French Amy, Punnett Angela, Garcia-Bournissen Facundo, Ito Shinya, Koren Gideon
Division of Clinical Pharmacology & Toxicology, Department of Paediatrics, The Hospital for Sick Children, Toronto, Ontario, Canada.
Can J Clin Pharmacol. 2010 Winter;17(1):e1-4. Epub 2010 Jan 4.
A case of unusual reactions consisting of involuntary abnormal facial movements in a child following exposure to the 5-HT3 receptor antagonists for prophylaxis against chemotherapy-induced vomiting is presented. Potential mechanisms for these reactions are discussed.
本文报告了1例儿童在使用5-HT3受体拮抗剂预防化疗引起的呕吐后出现不自主异常面部运动的罕见反应病例,并讨论了这些反应的潜在机制。