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一名横纹肌肉瘤患儿对5-羟色胺3（5-HT3）受体拮抗剂的异常反应。

Unusual reactions to 5-HT3 receptor antagonists in a child with rhabdomyosarcoma.

作者信息

Lee Candace Y W, Ratnapalan Savithiri, Thompson Margaret, Nathan Paul C, Closs Jordan, French Amy, Punnett Angela, Garcia-Bournissen Facundo, Ito Shinya, Koren Gideon

机构信息

Division of Clinical Pharmacology & Toxicology, Department of Paediatrics, The Hospital for Sick Children, Toronto, Ontario, Canada.

出版信息

Can J Clin Pharmacol. 2010 Winter;17(1):e1-4. Epub 2010 Jan 4.

PMID:20051608
Abstract

A case of unusual reactions consisting of involuntary abnormal facial movements in a child following exposure to the 5-HT3 receptor antagonists for prophylaxis against chemotherapy-induced vomiting is presented. Potential mechanisms for these reactions are discussed.

摘要

本文报告了1例儿童在使用5-HT3受体拮抗剂预防化疗引起的呕吐后出现不自主异常面部运动的罕见反应病例，并讨论了这些反应的潜在机制。

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Unusual reactions to 5-HT3 receptor antagonists in a child with rhabdomyosarcoma.一名横纹肌肉瘤患儿对5-羟色胺3（5-HT3）受体拮抗剂的异常反应。
Can J Clin Pharmacol. 2010 Winter;17(1):e1-4. Epub 2010 Jan 4.
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Palonosetron: a unique 5-HT3 receptor antagonist indicated for the prevention of acute and delayed chemotherapy-induced nausea and vomiting.帕洛诺司琼：一种独特的5-羟色胺3（5-HT3）受体拮抗剂，用于预防化疗引起的急性和迟发性恶心及呕吐。
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Preliminary experience with use of a selective 5HT3 receptor antagonist (ondansetron) to prevent high dose chemotherapy induced emesis.使用选择性5-羟色胺3（5HT3）受体拮抗剂（昂丹司琼）预防大剂量化疗所致呕吐的初步经验。
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Safety and efficacy of a continuous infusion, patient-controlled antiemetic pump for children receiving emetogenic chemotherapy.用于接受致吐性化疗的儿童的持续输注、患者自控式止吐泵的安全性和有效性。
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[From cocaine to innovative antiemetics. The medicinal chemistry of 5-ht3 receptor antagonists].[从可卡因到创新止吐药。5-羟色胺3受体拮抗剂的药物化学]
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Ondansetron to prevent vomiting after cancer chemotherapy.
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[Use of ondansetron, a 5-HT3 receptor antagonist, as a new type of antiemetic in pediatric oncology].5-羟色胺3受体拮抗剂昂丹司琼作为儿科肿瘤新型止吐药的应用
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