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一名横纹肌肉瘤患儿对5-羟色胺3(5-HT3)受体拮抗剂的异常反应。

Unusual reactions to 5-HT3 receptor antagonists in a child with rhabdomyosarcoma.

作者信息

Lee Candace Y W, Ratnapalan Savithiri, Thompson Margaret, Nathan Paul C, Closs Jordan, French Amy, Punnett Angela, Garcia-Bournissen Facundo, Ito Shinya, Koren Gideon

机构信息

Division of Clinical Pharmacology & Toxicology, Department of Paediatrics, The Hospital for Sick Children, Toronto, Ontario, Canada.

出版信息

Can J Clin Pharmacol. 2010 Winter;17(1):e1-4. Epub 2010 Jan 4.

Abstract

A case of unusual reactions consisting of involuntary abnormal facial movements in a child following exposure to the 5-HT3 receptor antagonists for prophylaxis against chemotherapy-induced vomiting is presented. Potential mechanisms for these reactions are discussed.

摘要

本文报告了1例儿童在使用5-HT3受体拮抗剂预防化疗引起的呕吐后出现不自主异常面部运动的罕见反应病例,并讨论了这些反应的潜在机制。

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