Department of Chemical Engineering, Konkuk University, Seoul, Korea.
J Mater Sci Mater Med. 2010 Apr;21(4):1143-9. doi: 10.1007/s10856-009-3980-1. Epub 2010 Jan 6.
Nanometer size biphasic calcium phosphate (BCP) powders with various Ca/P molar ratios satisfied with appropriate phase ratios of HA/beta-TCP were prepared by high temperature flame spray pyrolysis process. The BCP powders had spherical shapes and narrow size distributions irrespective of the ratios of Ca/P. The mean size of the BCP powders measured from the TEM image was 38 nm. The composition ratio of Ca/P was controlled from 1.500 to 1.723 in the spray solution, and required phase ratios of HA/TCP are controlled systematically. The calcium dissolution of the pellets obtained from the BCP powders directly prepared by flame spray pyrolysis in buffer solution increased with the decrease of Ca/P ratios except with the Ca/P ratio of 1.713. The pellet surface with Ca/P ratio of 1.500, which consisted of beta-TCP, was eroded dramatically for 7 days. On the other hand, the pellet surface with Ca/P ratio of 1.667 was stable and did not disintegrate after immersion in Tris-HCl buffer solution based on the SEM observation.
通过高温火焰喷雾热解法制备了具有不同 Ca/P 摩尔比的满足适当 HA/beta-TCP 相比例的纳米级双相磷酸钙 (BCP) 粉末。BCP 粉末具有球形形状和较窄的粒径分布，与 Ca/P 比无关。从 TEM 图像测量的 BCP 粉末的平均粒径为 38nm。喷雾溶液中 Ca/P 的组成比可控制在 1.500 至 1.723 之间，并可系统控制所需的 HA/TCP 相比例。直接通过火焰喷雾热解法从 BCP 粉末制备的微球在缓冲溶液中的钙溶解率随 Ca/P 比的降低而增加，除了 Ca/P 比为 1.713 时。Ca/P 比为 1.500 的微球表面由 beta-TCP 组成，在 7 天内急剧侵蚀。另一方面，基于 SEM 观察，Ca/P 比为 1.667 的微球表面在 Tris-HCl 缓冲溶液中浸泡后稳定且未分解。
Zotero 插件