Dhillon I, Zouzias D, Geronemus R
Department of Dermatology, New York University Medical Center, New York 10016.
J Dermatol Surg Oncol. 1991 Mar;17(3):300-2. doi: 10.1111/j.1524-4725.1991.tb03647.x.
A patient with epidermodysplasia verruciformis died of intracranial invasion by squamous cell carcinoma (SCC). A biopsy of clinically normal skin had revealed perineural invasion by malignant keratinocytes. Because SCCs arising in patients with epidermodysplasia verruciformis may be biologically aggressive, it is best to excise them with careful control of the surgical tissue margins.
