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卡培他滨和西妥昔单抗对疣状表皮发育不良患者难治性会阴转移性鳞状细胞癌的姑息作用。

Palliative effect of capecitabine and cetuximab for refractory metastatic squamous cell carcinoma of the perineum in epidermodysplasia verruciformis.

作者信息

Lynch Michael C, Drabick Joseph J, Neves Rogerio I, Fox Edward J, Mackley Heath B, Anderson Bryan E

出版信息

Skinmed. 2014 Jan-Feb;12(1):54-6.

PMID:24720087
Abstract

A teenage girl presented with multiple warty skin lesions and had a diagnosis of epidermodysplasia verruciformis made several years later. Later in life she presented with an extensive SCC in situ in her gluteal crease that was surgically resected with wide margins. Despite this treatment, the lesion recurred with extension onto her lower back. Biopsies at the time confirmed SCC in situ of the perianal tissue and invasive SCC above her gluteal cleft.

摘要

一名青少年女性出现多发性疣状皮肤病变,数年后被诊断为疣状表皮发育不良。在其成年后,她的臀沟处出现了广泛的原位鳞状细胞癌,并接受了手术切除,切缘较宽。尽管进行了这种治疗,病变仍复发并蔓延至她的下背部。当时的活检证实肛周组织为原位鳞状细胞癌,臀裂上方为浸润性鳞状细胞癌。

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