Suppr超能文献

胃癌——经济欠发达地区面临的一大挑战。

Gastric carcinoma--a big challenge in a poor economy.

作者信息

Osime O Clement, Momoh M I, Irowa O O, Obumse A

机构信息

Department of Surgery, University of Benin Teaching Hospital, PMB 1111, Benin City, Nigeria.

出版信息

J Gastrointest Cancer. 2010 Jun;41(2):101-6. doi: 10.1007/s12029-009-9118-3.

Abstract

BACKGROUND

Gastric carcinoma is usually characterized with significant morbidity and mortality mainly because of late presentation. Late presentation of gastric carcinoma is a prominent feature in developing and poor countries.

AIM OF STUDY

The purpose of this study is to present our experience with the pattern and outcome of gastric tumors at the University of Benin Teaching Hospital, Benin City, Nigeria; with emphasis on late presentation of the patients.

PATIENTS AND METHODS

The case files of the patients that were managed at the University of Benin Teaching Hospital for gastric tumors over a 5-year period (January 2004 to December 2006) were analyzed for biodata, symptoms and signs of disease, findings at operation, treatment offered, and outcome of treatment.

RESULTS

The male/female ratio was 2.3:1, with the youngest patient being 38 years while the oldest patient was 76 years old. Upper abdominal pain and a palpable mass per abdomen were the commonest symptoms and signs, respectively. Alcohol ingestion was the commonest identifiable risk factor. Only 30.4% of the patients presented within a year of the onset of symptoms. The gastric antrum was affected in over 78% of the cases, and adenocarcinoma was found in about 90% of the patients. Partial gastrectomy with gastrojejunostomy was the commonest procedure carried out. The mortality rate was 39.1%, and of the patients that died, 66.7% occurred within a year from time of diagnosis.

CONCLUSION

Most of the cases of gastric carcinoma presented in this study presented late with associated significant mortality. Health education is advised with a view to encouraging early presentation.

摘要

背景

胃癌通常具有较高的发病率和死亡率,主要原因是就诊延迟。在发展中国家和贫困国家,胃癌就诊延迟是一个突出特征。

研究目的

本研究的目的是介绍我们在尼日利亚贝宁城贝宁大学教学医院处理胃肿瘤的模式和结果的经验;重点是患者的就诊延迟情况。

患者和方法

分析了在贝宁大学教学医院5年期间(2004年1月至2006年12月)接受治疗的胃肿瘤患者的病历,包括生物数据、疾病症状和体征、手术发现、所提供的治疗以及治疗结果。

结果

男女比例为2.3:1,最年轻的患者38岁,最年长的患者76岁。上腹部疼痛和腹部可触及肿块分别是最常见的症状和体征。饮酒是最常见的可识别风险因素。只有30.4%的患者在症状出现后一年内就诊。超过78%的病例胃窦受累,约90%的患者发现腺癌。胃部分切除术加胃空肠吻合术是最常见的手术。死亡率为39.1%,在死亡患者中,66.7%在诊断后一年内死亡。

结论

本研究中的大多数胃癌病例就诊延迟,伴有显著的死亡率。建议开展健康教育,以鼓励早期就诊。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验