Department of Neuroradiology, Centre Hospitalier Sainte-Anne, Paris, France.
AJNR Am J Neuroradiol. 2010 Sep;31(8):1504-5. doi: 10.3174/ajnr.A1978. Epub 2010 Jan 6.
The multiplicity of meningiomas or abrupt lesion growth in patients treated with cyproterone acetate suggests that this progestative treatment may promote lesion growth. We report the rapid regression of an incidental meningioma after discontinuation of a 10-year cyproterone acetate treatment. This unique observation suggests that conservative management of meningiomas may be the best option among users of high doses of cyproterone acetate, given that spontaneous regression may occur after hormonal treatment discontinuation.
环丙孕酮治疗的患者中脑膜瘤的多发性或病变突然增大表明这种孕激素治疗可能会促进病变生长。我们报告了一例偶然发现的脑膜瘤在停止使用环丙孕酮治疗 10 年后的快速消退。这一独特的观察结果表明，对于使用大剂量环丙孕酮的患者，脑膜瘤的保守治疗可能是最佳选择，因为在激素治疗停止后可能会发生自发消退。
