Department of Radiology and Research Institute of Radiology, University of Ulsan College of Medicine, Asan Medical Center, Songpa-Gu, Seoul, Korea.
AJNR Am J Neuroradiol. 2010 Jun;31(6):1113-7. doi: 10.3174/ajnr.A1970. Epub 2010 Jan 6.
The safety and efficacy of SBCAS have not been evaluated in detail. The purpose of our study was to evaluate the outcome after SBCAS in high-risk patients compared with unilateral stent placement.
Between March 2002 and October 2008, a total of 205 consecutive high-risk patients underwent CAS at our institution. Of these patients, 30 (14.6%) underwent SBCAS (n = 24) and staged SBCAS (n = 6). Patients who underwent unilateral CAS (n = 175) during the same period served as controls. The stroke risk factors, procedural results, and outcome at 30 days and 6 months, as well as the restenosis rate at 6 months, were compared by using either the chi(2) test or the Kruskal-Wallis equality-of-populations rank test.
Our data revealed no significant differences in the stroke risk factors between the SBCAS and the control group. HPS occurred more commonly in SBCAS (ie, 16.7%, 4/24) compared with 2.9% (5/175) in the control group (P = .014). However, there was no statistical significance between 2 groups in the event rate of stroke (minor and/or major stroke), death, or restenosis at 6 months.
There was no significant difference in outcome at 6 months following stent placement between SBCAS and unilateral CAS in the high-risk patient group, even though HPS occurred more commonly after SBCAS.
SBCAS 的安全性和有效性尚未得到详细评估。本研究的目的是评估与单侧支架置入相比,SBCAS 在高危患者中的治疗效果。
2002 年 3 月至 2008 年 10 月,我院共对 205 例高危患者进行了 CAS。其中,30 例(14.6%)患者接受了 SBCAS(n=24)和分期 SBCAS(n=6)。同期行单侧 CAS(n=175)的患者作为对照组。采用卡方检验或 Kruskal-Wallis 等方差秩检验比较两组患者的中风危险因素、手术结果、30 天和 6 个月的治疗效果,以及 6 个月的再狭窄率。
SBCAS 组和对照组患者的中风危险因素无显著差异。SBCAS 组更常见 HPS(16.7%,4/24),而对照组为 2.9%(5/175)(P=.014)。然而,两组患者的中风(轻微和/或主要中风)、死亡或 6 个月时再狭窄的发生率无统计学差异。
高危患者中,SBCAS 与单侧 CAS 支架置入 6 个月的治疗效果无显著差异,尽管 SBCAS 后 HPS 更常见。