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HIV相关疾病管理中的争议

Controversies in the management of HIV-related illnesses.

作者信息

Cooke M, Libman H, Smith M D, Cooney T G, Hollander H, Makadon H J, Volberding P A

机构信息

Department of Medicine, University of California, San Francisco.

出版信息

J Gen Intern Med. 1991 Jan-Feb;6(1 Suppl):S46-55. doi: 10.1007/BF02599258.

DOI:10.1007/BF02599258
PMID:2005478
Abstract

The care of patients who have HIV infection requires technical competence, skill in clinical decision making, a commitment to continuing self-education, the ability to collaborate with medical and community-based service providers, and attention to the psychological and ethical aspects of patient care. General internists bring these attributes to their work and will be increasingly involved in meeting the challenges presented by the AIDS epidemic. Controversial issues in the management of HIV illness include: assessment and management of latent syphilis in patients with intercurrent HIV infection; risk assessment and postexposure zidovudine prophylaxis of health care workers after occupational accidents; determination of the risk of reactivation tuberculosis in HIV-infected individuals; and treatment or nontreatment of infections with the Mycobacterium avium complex in symptomatic patients. Patients illustrating these management problems are presented by progressive disclosure; the points made in discussion by a panel of general internists and AIDS specialists are presented.

摘要

对感染艾滋病毒患者的护理需要专业技能、临床决策能力、持续自我教育的决心、与医疗及社区服务提供者协作的能力,以及对患者护理心理和伦理方面的关注。普通内科医生具备这些特质,并将越来越多地参与应对艾滋病流行带来的挑战。艾滋病毒疾病管理中的争议性问题包括:并发艾滋病毒感染患者潜伏梅毒的评估与管理;医护人员职业事故后齐多夫定暴露后预防的风险评估;艾滋病毒感染者结核复发风险的判定;有症状患者鸟分枝杆菌复合体感染的治疗或不治疗。通过逐步披露呈现说明这些管理问题的患者;展示普通内科医生和艾滋病专家小组在讨论中提出的观点。

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Controversies in the management of HIV-related illnesses.HIV相关疾病管理中的争议
J Gen Intern Med. 1991 Jan-Feb;6(1 Suppl):S46-55. doi: 10.1007/BF02599258.
2
Incidence and natural history of Mycobacterium avium-complex infections in patients with advanced human immunodeficiency virus disease treated with zidovudine. The Zidovudine Epidemiology Study Group.接受齐多夫定治疗的晚期人类免疫缺陷病毒病患者鸟分枝杆菌复合群感染的发病率和自然史。齐多夫定流行病学研究组。
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引用本文的文献

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Quality in HIV/AIDS care. Specialty-related or experience-related?艾滋病护理的质量。与专业相关还是与经验相关?
J Gen Intern Med. 1997 Mar;12(3):195-7. doi: 10.1007/s11606-006-5030-8.

本文引用的文献

1
Central nervous system disease in acquired immunodeficiency syndrome: prospective correlation using CT, MR imaging, and pathologic studies.获得性免疫缺陷综合征中的中枢神经系统疾病:CT、磁共振成像与病理研究的前瞻性相关性
Radiology. 1986 Jan;158(1):141-8. doi: 10.1148/radiology.158.1.3940372.
2
Evidence for early central nervous system involvement in the acquired immunodeficiency syndrome (AIDS) and other human immunodeficiency virus (HIV) infections. Studies with neuropsychologic testing and magnetic resonance imaging.获得性免疫缺陷综合征(艾滋病)及其他人类免疫缺陷病毒(HIV)感染早期中枢神经系统受累的证据。神经心理学测试和磁共振成像研究。
Ann Intern Med. 1987 Dec;107(6):828-36. doi: 10.7326/0003-4819-107-6-828.
3
Tuberculosis in patients with the acquired immunodeficiency syndrome. Clinical features, response to therapy, and survival.
获得性免疫缺陷综合征患者的结核病。临床特征、治疗反应及生存情况。
Am Rev Respir Dis. 1987 Sep;136(3):570-4. doi: 10.1164/ajrccm/136.3.570.
4
Syphilis in the AIDS era.艾滋病时代的梅毒
N Engl J Med. 1987 Jun 18;316(25):1600-1. doi: 10.1056/NEJM198706183162510.
5
Alteration in the natural history of neurosyphilis by concurrent infection with the human immunodeficiency virus.人类免疫缺陷病毒合并感染对神经梅毒自然病程的影响。
N Engl J Med. 1987 Jun 18;316(25):1569-72. doi: 10.1056/NEJM198706183162503.
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Mycobacterioses and the acquired immunodeficiency syndrome. Joint Position Paper of the American Thoracic Society and the Centers for Disease Control.
Am Rev Respir Dis. 1987 Aug;136(2):492-6. doi: 10.1164/ajrccm/136.2.492.
7
Improved detection of Mycobacterium avium complex with the Bactec radiometric system.使用Bactec放射测量系统改进鸟分枝杆菌复合群的检测。
Diagn Microbiol Infect Dis. 1988 May;10(1):1-6. doi: 10.1016/0732-8893(88)90121-6.
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Recommendations for diagnosing and treating syphilis in HIV-infected patients.
MMWR Morb Mortal Wkly Rep. 1988 Oct 7;37(39):600-2, 607-8.
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Update: acquired immunodeficiency syndrome and human immunodeficiency virus infection among health-care workers.
MMWR Morb Mortal Wkly Rep. 1988 Apr 22;37(15):229-34, 239.
10
Neuropsychological outcome of zidovudine (AZT) treatment of patients with AIDS and AIDS-related complex.齐多夫定(AZT)治疗艾滋病及艾滋病相关综合征患者的神经心理学转归
N Engl J Med. 1988 Dec 15;319(24):1573-8. doi: 10.1056/NEJM198812153192404.