Department of Oral Pathology, King's College London Dental Institute at Guy's, King's College and St Thomas' Hospitals, London, United Kingdom.
Head Neck. 2010 Oct;32(10):1310-20. doi: 10.1002/hed.21326.
There is a lack of consensus about the appropriate treatment of ranula. The objective of the present investigation was to produce a scientific basis for treatment.
A review of the relevant literature is interpreted in the light of improved knowledge about the local anatomy and the pathophysiology of the salivary glands.
The oral and plunging ranulas are cystic extravasation mucoceles that arise from the sublingual gland and usually from a torn duct of Rivinus. The sublingual gland is a spontaneous secretor and the salivary flow is resistant to obstruction, which is caused by fibrosis induced by the extravasation. The submandibular gland is not a spontaneous secretor, is less resistant, and does not give rise to ranulas.
Effective treatment is removal of the involved unit of the sublingual gland or inducing sufficient fibrosis to seal the leak through which the mucus extravasates.
关于如何恰当地治疗舌下腺囊肿,目前尚无定论。本研究旨在为治疗提供科学依据。
根据局部解剖学和唾液腺生理学知识的进展,对相关文献进行了复习。
口外型和哑铃型舌下腺囊肿是由舌下腺的黏液外渗导致的囊性黏液囊肿,通常由撕裂的瑞氏(Rivinus)导管引起。舌下腺是一个自发性分泌腺,其分泌液不易受阻,即使受阻,也只是由于黏液外渗导致的纤维化所致。下颌下腺不是自发性分泌腺,分泌液较易受阻,且不会引起舌下腺囊肿。
有效的治疗方法是切除受累的舌下腺单位,或通过诱导足够的纤维化使外渗的黏液封闭漏口。