Department of Dermatology, University of Illinois at Chicago, Chicago, IL, USA.
Clin Exp Dermatol. 2009 Dec;34(8):e722-5. doi: 10.1111/j.1365-2230.2009.03448.x.
We report an unusual case of localized cutaneous nodules heralding the recurrence of systemic CD30+ anaplastic large-cell lymphoma (ALCL). A 47-year-old woman developed numerous violaceous nodules in the perineal and upper thigh area 3 years after multimodal treatment and complete remission of primary anaplastic large-cell CD30+ lymphoma. Using immunohistochemical and T-cell gene rearrangement analysis, a recurrence of her anaplastic large-cell lymphoma was diagnosed.
我们报告了一例不常见的局部皮肤结节病例，预示着全身性 CD30+ 间变性大细胞淋巴瘤 (ALCL) 的复发。一名 47 岁女性在原发性间变性大细胞 CD30+ 淋巴瘤经多模式治疗和完全缓解后 3 年，于会阴部和大腿上部出现多个紫红色结节。通过免疫组织化学和 T 细胞基因重排分析，诊断为间变性大细胞淋巴瘤复发。
