Department of Dermatology, Kinki University School of Medicine, Osaka, Japan.
Clin Exp Dermatol. 2009 Dec;34(8):e833-6. doi: 10.1111/j.1365-2230.2009.03574.x.
Lichen amyloidosus (LA) is a type of primary localized cutaneous amyloidosis characterized by multiple pruritic discrete hyperkeratotic papules with amyloid deposition in the papillary dermis. Clinical regression is usually difficult to achieve, even after treatment. In this study, we report a case of an adult man with LA associated with atopic dermatitis (AD) which was successfully treated with narrowband ultraviolet B (NB-UVB) phototherapy, topical corticosteroids and an oral antihistamine. This case suggests that NB-UVB phototherapy may be a useful adjuvant for LA associated with AD.
淀粉样变苔藓(LA)是一种原发性局限性皮肤淀粉样变性,其特征是在乳头真皮中有淀粉样物质沉积的多个瘙痒性离散性角化过度丘疹。即使经过治疗,临床消退通常也很难实现。在本研究中,我们报告了一例成人 LA 伴特应性皮炎(AD)的病例,该病例经窄带紫外线 B(NB-UVB)光疗、局部皮质类固醇和口服抗组胺药治疗后成功治愈。该病例表明,NB-UVB 光疗可能是治疗 LA 伴 AD 的一种有效辅助手段。