Center for American Indian Health, Johns Hopkins Bloomberg School of Public Health, 621 N. Wolfe Street, Baltimore, MD 21205, USA.
Epidemiol Infect. 2010 Aug;138(8):1146-54. doi: 10.1017/S0950268809991464. Epub 2010 Jan 8.
Few population-based studies have investigated the epidemiology of adult community-acquired pneumonia (CAP). We aimed to determine the incidence of CAP in a population at high-risk for pneumococcal disease and to evaluate a standardized method for interpreting chest radiographs adapted from the World Health Organization paediatric chest radiograph interpretation guidelines. We reviewed radiology records at the two healthcare facilities serving the White Mountain Apache tribe to identify possible pneumonia cases > or =40 years of age. We categorized patients with clinical criteria and a physician diagnosis of pneumonia as clinical CAP and those with clinical criteria and an acute infiltrate as radiographic CAP. We identified 100 (27/1000 person-years) and 60 (16/1000 person-years) episodes of clinical and radiographic CAP, respectively. The incidence of CAP increased with age. Both radiographic and clinical CAP were serious illnesses with more than half of patients hospitalized. Our case definitions and methods may be useful for comparing data across studies and conducting vaccine trials.
很少有基于人群的研究调查过成人社区获得性肺炎（CAP）的流行病学。我们的目的是确定在高危人群中肺炎球菌病的发病率，并评估一种标准化的方法来解读胸片，该方法改编自世界卫生组织儿科胸片解读指南。我们回顾了为怀特山阿帕切部落提供服务的两家医疗机构的放射学记录，以确定年龄大于或等于 40 岁的可能患有肺炎的病例。我们将有临床标准和医生诊断为肺炎的患者归类为临床 CAP，将有临床标准和急性浸润的患者归类为放射学 CAP。我们分别确定了 100 例（1000 人年中 27 例）和 60 例（1000 人年中 16 例）临床和放射学 CAP 病例。CAP 的发病率随年龄增长而增加。放射学和临床 CAP 都是严重疾病，超过一半的患者住院治疗。我们的病例定义和方法可能有助于比较研究数据并进行疫苗试验。
