Department of Epidemiology, Ilam University of Medical Sciences, Ilam, Iran.
QJM. 2010 May;103(5):285-92. doi: 10.1093/qjmed/hcp182. Epub 2010 Jan 7.
Leukocytosis (raised concentration of white cells in the blood) is commonly associated with infection or inflammation, but can occur in a wide variety of other conditions. Leukocytosis has also been linked with increased mortality and morbidity in a number of studies. We have systematically reviewed the relevant literature, which clearly demonstrates an association between leukocytosis and mortality-particularly due to cardiovascular or cerebrovascular causes. The mechanisms of this effect are uncertain but, when combined with other markers predictive of death, leukocytosis may contribute to modelling systems to predict in-patient mortality risk.
白细胞增多症（血液中白细胞浓度升高）通常与感染或炎症有关，但也可能发生在许多其他情况下。多项研究表明，白细胞增多症与死亡率和发病率的增加有关。我们系统地回顾了相关文献，这些文献清楚地表明白细胞增多症与死亡率之间存在关联，尤其是与心血管或脑血管原因有关。这种影响的机制尚不确定，但当与其他预测死亡的标志物结合使用时，白细胞增多症可能有助于建立预测住院患者死亡风险的模型系统。
