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1
Point: Pulmonary edema does occur in human athletes performing heavy sea-level exercise.观点：在海平面进行高强度运动的人类运动员中确实会发生肺水肿。
J Appl Physiol (1985). 2010 Oct;109(4):1270-2. doi: 10.1152/japplphysiol.01353.2009. Epub 2010 Jan 7.
2
Counterpoint: Pulmonary edema does not occur in human athletes performing heavy sea-level exercise.反驳观点：在海平面进行高强度运动的人类运动员不会发生肺水肿。
J Appl Physiol (1985). 2010 Oct;109(4):1272-3. doi: 10.1152/japplphysiol.01353.2009a.
3
Edema in athletes vs. interstitial edema in anyone.运动员的水肿与任何人的间质性水肿。
J Appl Physiol (1985). 2010 Oct;109(4):1277; discussion 1281-2. doi: 10.1152/japplphysiol.00814.2010.
4
Pulmonary edema in athletes: methodology or meaningful physiology?运动员中的肺水肿：是方法学问题还是有意义的生理学现象？
J Appl Physiol (1985). 2010 Oct;109(4):1277-8; discussion 1281-2. doi: 10.1152/japplphysiol.00814.2010.
5
Mild interstitial pulmonary edema occurs during sea level strenuous exercise.轻度间质性肺水肿发生于海平面剧烈运动期间。
J Appl Physiol (1985). 2010 Oct;109(4):1276; discussion 1281-2. doi: 10.1152/japplphysiol.00814.2010.
6
Rebuttal from Hopkins.来自霍普金斯大学的反驳。
J Appl Physiol (1985). 2010 Oct;109(4):1273-4. doi: 10.1152/japplphysiol.01353.2009b.
7
Rebuttal from Sheel and McKenzie.希尔和麦肯齐的反驳。
J Appl Physiol (1985). 2010 Oct;109(4):1274-5. doi: 10.1152/japplphysiol.01353.2009c.
8
Exercise-induced pulmonary edema—the debate continues.运动性肺水肿——争论仍在继续。
J Appl Physiol (1985). 2010 Oct;109(4):1279-80; discussion 1281-2. doi: 10.1152/japplphysiol.00814.2010.
9
Pulmonary edema following exercise: an individual response?运动后肺水肿：个体反应？
J Appl Physiol (1985). 2010 Oct;109(4):1278-9; discussion 1281-2. doi: 10.1152/japplphysiol.00814.2010.
10
Interstitial edema does occur with limited adverse effect in the long term.间质水肿确实会发生，从长期来看不良反应有限。
J Appl Physiol (1985). 2010 Oct;109(4):1279; discussion 1281-2. doi: 10.1152/japplphysiol.00814.2010.

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Sex differences in exercise-induced arterial hypoxemia and pulmonary edema following high-intensity exercise in highly trained endurance athletes.高水平耐力运动员高强度运动后运动诱导的动脉低氧血症和肺水肿中的性别差异。
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The impact of heterogeneity of the air-blood barrier on control of lung extravascular water and alveolar gas exchange.气血屏障异质性对肺血管外水分控制及肺泡气体交换的影响。
Front Netw Physiol. 2023 May 11;3:1142245. doi: 10.3389/fnetp.2023.1142245. eCollection 2023.
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A neoprene vest hastens dyspnoea and leg fatigue during exercise testing: entangled breathing and cardiac hindrance?氯丁橡胶背心在运动试验中加速呼吸困难和腿部疲劳：呼吸缠绕和心脏受阻？
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Int J Environ Res Public Health. 2020 May 17;17(10):3501. doi: 10.3390/ijerph17103501.
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Heavy upright exercise increases ventilation-perfusion mismatch in the basal lung: indirect evidence for interstitial pulmonary edema.剧烈的直立运动增加基底肺的通气-灌注不匹配：间质性肺水肿的间接证据。
J Appl Physiol (1985). 2019 Aug 1;127(2):473-481. doi: 10.1152/japplphysiol.00056.2019. Epub 2019 Jun 27.
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Pulmonary and Respiratory Muscle Function in Response to Marathon and Ultra-Marathon Running: A Review.马拉松和超长马拉松跑对呼吸和呼吸肌功能的影响：综述。
Sports Med. 2019 Jul;49(7):1031-1041. doi: 10.1007/s40279-019-01105-w.
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Pulmonary Aspects of Exercise and Sports.运动与体育的肺部相关问题
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Lung injury related to extreme environments.与极端环境相关的肺损伤。
Eur Respir Rev. 2014 Dec;23(134):416-26. doi: 10.1183/09059180.00006214.

本文引用的文献

1
Counterpoint: Pulmonary edema does not occur in human athletes performing heavy sea-level exercise.反驳观点：在海平面进行高强度运动的人类运动员不会发生肺水肿。
J Appl Physiol (1985). 2010 Oct;109(4):1272-3. doi: 10.1152/japplphysiol.01353.2009a.
2
Rapid intravenous infusion of 20 ml/kg saline does not impair resting pulmonary gas exchange in the healthy human lung.快速静脉输注 20 毫升/公斤生理盐水不会损害健康人肺部的静息肺气体交换。
J Appl Physiol (1985). 2010 Jan;108(1):53-9. doi: 10.1152/japplphysiol.00787.2009. Epub 2009 Nov 12.
3
Pulmonary perfusion heterogeneity is increased by sustained, heavy exercise in humans.在人类中，持续的剧烈运动增加了肺灌注的异质性。
J Appl Physiol (1985). 2009 Nov;107(5):1559-68. doi: 10.1152/japplphysiol.00491.2009. Epub 2009 Sep 10.
4
Lung density is not altered following intense normobaric hypoxic interval training in competitive female cyclists.在竞技女性自行车运动员中，进行高强度常压低氧间歇训练后，肺密度未发生改变。
J Appl Physiol (1985). 2007 Sep;103(3):875-82. doi: 10.1152/japplphysiol.00247.2007. Epub 2007 Jun 14.
5
Human lung density is not altered following normoxic and hypoxic moderate-intensity exercise: implications for transient edema.常氧和低氧中等强度运动后人体肺密度未改变：对短暂性水肿的影响
J Appl Physiol (1985). 2007 Jul;103(1):111-8. doi: 10.1152/japplphysiol.01087.2006. Epub 2007 Apr 5.
6
An ultracyclist with pulmonary edema during the Bicycle Race Across America.一名在横贯美国自行车赛期间出现肺水肿的超级自行车运动员。
Med Sci Sports Exerc. 2007 Jan;39(1):8-12. doi: 10.1249/01.mss.0000235885.79110.79.
7
Exercise induced arterial hypoxemia: the role of ventilation-perfusion inequality and pulmonary diffusion limitation.运动诱发的动脉血氧不足：通气-灌注不均及肺弥散受限的作用
Adv Exp Med Biol. 2006;588:17-30. doi: 10.1007/978-0-387-34817-9_3.
8
The effect of sustained heavy exercise on the development of pulmonary edema in trained male cyclists.持续高强度运动对训练有素的男性自行车运动员肺水肿发展的影响。
Respir Physiol Neurobiol. 2005 Feb 15;145(2-3):209-18. doi: 10.1016/j.resp.2004.06.010.
9
Swimming-induced pulmonary edema: clinical presentation and serial lung function.游泳诱发的肺水肿：临床表现与系列肺功能
Chest. 2004 Aug;126(2):394-9. doi: 10.1378/chest.126.2.394.
10
Decreased lung capillary blood volume post-exercise is compensated by increased membrane diffusing capacity.运动后肺毛细血管血容量的减少通过膜弥散能力的增加得到补偿。
Eur J Appl Physiol. 2004 Oct;93(1-2):96-101. doi: 10.1007/s00421-004-1170-x. Epub 2004 Jul 24.

Point: Pulmonary edema does occur in human athletes performing heavy sea-level exercise.

作者信息

Hopkins Susan R

机构信息

Division of Physiology, Department of Medicine, University of California San Diego, La Jolla, California, USA.

出版信息

J Appl Physiol (1985). 2010 Oct;109(4):1270-2. doi: 10.1152/japplphysiol.01353.2009. Epub 2010 Jan 7.

DOI:10.1152/japplphysiol.01353.2009
PMID:20056844
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3774213/
Abstract
摘要