Division of Research, Kaiser Permanente Medical Care Program, Oakland, CA 94612, USA.
Med Care. 2010 Feb;48(2):133-9. doi: 10.1097/MLR.0b013e3181c15a6e.
Variance reduction is sometimes considered as a goal of clinical quality improvement. Variance among physicians, hospitals, or health plans has been evaluated as the proportion of total variance (or intraclass correlation, ICC) in a quality measure; low ICCs have been interpreted to indicate low potential for quality improvement at that level. However, the absolute amount of variation, expressed in clinically meaningful units, is less frequently reported. Moreover, changes in variance components have not been studied as quality improves.
To examine changes in variance components at primary care physician and medical facility levels as performance improved for 4 quality indicators: systolic blood pressure levels in hypertension; low-density lipoprotein-cholesterol levels in hyperlipidemia; patient-reported care experience scores after primary care visits; and mammography screening rates.
Adult members (n = 62,596-410,976) of Kaiser Permanente in Northern California, served by more than 1000 primary care physicians in 35 facilities, from 2001 to 2006.
Multilevel linear and logistic regression to examine the interphysician and interfacility variances in 4 quality indicators over 6 years, after case-mix adjustment.
ICCs were low for all 4 indicators at both levels (0.0021-0.086). Nevertheless, variances at both levels were statistically and clinically significant. For systolic blood pressure and the care experience score, interfacility and interphysician variance as well as ICCs decreased further as quality improved; declines were greater at the facility level. For low-density lipoprotein-cholesterol, variability at both levels increased with quality improvement; and for screening mammography, small declines were not statistically significant for either physicians or facilities.
Low proportions of variance do not predict low potential for quality improvement. Despite low ICCs for facilities, quality improvement efforts directed primarily at facilities improved quality for all 4 indicators.
方差减少有时被视为临床质量改进的目标。医生、医院或医疗计划之间的差异已被评估为质量衡量标准中的总方差(或组内相关系数,ICC)的比例;低 ICC 被解释为表明该水平的质量改进潜力较低。然而,以临床有意义的单位表示的绝对变化量报告较少。此外,在质量提高的过程中,方差分量的变化尚未得到研究。
检查在 4 项质量指标(高血压患者的收缩压水平;高脂血症患者的低密度脂蛋白胆固醇水平;初级保健就诊后患者报告的护理体验评分;和乳房 X 光筛查率)的表现提高时,基层保健医生和医疗设施水平的方差分量的变化。
来自加利福尼亚州北部 Kaiser Permanente 的成年成员(n = 62596-410976),由 35 个设施中的 1000 多名基层保健医生提供服务,时间跨度为 2001 年至 2006 年。
使用多层次线性和逻辑回归,在经过病例组合调整后,在 6 年内检查 4 项质量指标的医生间和设施间方差。
所有 4 项指标在两个层面上的 ICC 都很低(0.0021-0.086)。尽管如此,两个层面上的方差在统计学上和临床上都有意义。对于收缩压和护理体验评分,随着质量的提高,设施间和医生间的方差以及 ICC 进一步降低;下降在设施层面上更为明显。对于低密度脂蛋白胆固醇,随着质量的提高,两个层面上的变异性都增加了;而对于乳房 X 光筛查,医生和设施层面的小幅度下降都没有统计学意义。
低比例的方差并不预示着质量改进的潜力低。尽管设施的 ICC 较低,但主要针对设施的质量改进工作提高了所有 4 项指标的质量。