Division of Hematoocology, Department of Internal Medicine, College of Medicine, Yeungnam University, Daegu, Korea.
Cancer Res Treat. 2009 Dec;41(4):241-4. doi: 10.4143/crt.2009.41.4.241. Epub 2009 Dec 31.
Chondroblastoma is a rare benign cartilaginous neoplasm that accounts for approximately 1% of all bone tumors and characteristically arises in the epiphysis of a long bone, particularly the humerus, tibia, and femur. Chondroblastoma can affect people of all ages. It is, however, most common in children and young adults between the ages of 10 and 20 years. Although most chondroblastomas are cured by limited surgical procedures, occasional lesions behave more aggressively and may even metastasis. In this case a young man with pulmonary metastatic chondroblastoma on spine is presented. Unlike previously published examples of metastatic chondroblastoma, these metastasis developed before any operative manipulation of the primary tumor. And primary tumor site was also unusual. The histologic characteristics of the primary, metastatic tumors were those of a conventional chondroblastoma.
成软骨细胞瘤是一种罕见的良性软骨性肿瘤,约占所有骨肿瘤的 1%,特征性地发生于长骨的骨骺,特别是肱骨、胫骨和股骨。成软骨细胞瘤可发生于所有年龄段的人群。然而,它最常见于 10 至 20 岁的儿童和年轻成人。尽管大多数成软骨细胞瘤通过有限的手术治疗即可治愈,但偶尔也会出现更具侵袭性的病变,甚至可能转移。在此病例中,我们报告了一例脊柱肺部转移性成软骨细胞瘤的年轻男性患者。与之前发表的转移性成软骨细胞瘤的病例不同,这些转移发生在原发性肿瘤的任何手术操作之前。而且,原发性肿瘤部位也不常见。原发性和转移性肿瘤的组织学特征均为常规成软骨细胞瘤。