Dipartimento di Radiologia e Cardiologia, Azienda Ospedaliero-Universitaria, Parma, Italy.
Radiol Med. 2010 Feb;115(1):36-50. doi: 10.1007/s11547-010-0483-6.
This study was undertaken to estimate surplus radiation dose in retrospectively electrocardiography (ECG)-gated dual-source computed tomography coronary angiography (DSCT-CA) due to the slope-up and slope-down of the tube current using prospectively ECG-triggered tube modulation.
We used an anthropomorphic phantom with an ECG-gated retrospective protocol and a DSCT scanner (Definition, Siemens). We used four tube current modulation algorithms: narrow pulsing window, with tube current reduction to 20% (A) and 4% (B) of peak current; and wide pulsing window, with tube current reduction to 20% (C) and 4% (D). Each algorithm was applied at five heart rates (HR=45, 60, 75, 90 and 120 bpm) with adaptive pitch values (0.2-0.5). Data sets were reconstructed in 5% increments from 0-95% of the R-R interval. Noise was measured at each R-R step in order to identify low noise (100% dose), medium noise (slope-up/down) and high noise (4/20% dose). Width of the transition window (slope-up/slope-down from 4/20% to 100% dose) was calculated. The surplus dose due to slope-up/slope-down was calculated.
Surplus dose was 19% (A), 34% (B), 14% (C) and 21% (D). The transition window lasted 10%+10% (slope-up + down) for HR <75 bpm and all HR in C (except for 120 bpm; 25%+15%), 15%+15% for HR >90 bpm (A). For C and D, instead, the slope-up increased with progressively higher HR (10%-25% of the R-R interval, except for 90 bpm, 10%), whereas the slope-down remained constant at 5% (except for 120 bpm; 10%).
The adaptive ECG-pulsing windows produced an increment of the surplus dose with increasing HR. The transition window was a constant source of surplus radiation dose in the range of 14%-34%.
本研究旨在评估因前瞻性心电图(ECG)触发管调制而使用斜率上升和斜率下降的管电流对 retrospectively ECG-gated 双源计算机断层冠状动脉造影(DSCT-CA)的额外辐射剂量。
我们使用带有 ECG-gated 回顾性协议的人体模型和 DSCT 扫描仪(Definition,Siemens)。我们使用了四种管电流调制算法:窄脉冲窗口,管电流降低至峰值电流的 20%(A)和 4%(B);宽脉冲窗口,管电流降低至峰值电流的 20%(C)和 4%(D)。每个算法在五个心率(HR=45、60、75、90 和 120 bpm)和自适应螺距值(0.2-0.5)下应用。数据集以 5%的增量从 RR 间隔的 0-95%重建。为了确定低噪声(100%剂量)、中噪声(斜率上升/下降)和高噪声(4/20%剂量),在每个 RR 步骤测量噪声。计算从 4/20%到 100%剂量的斜率上升/下降的过渡窗宽度。计算由于斜率上升/下降而导致的额外剂量。
额外剂量为 19%(A)、34%(B)、14%(C)和 21%(D)。对于 HR <75 bpm 的过渡窗持续时间为 10%+10%(斜率上升+下降),对于 C 则持续所有 HR(除了 120 bpm;25%+15%),对于 HR >90 bpm(A)为 15%+15%。对于 C 和 D,相反,斜率上升随着 HR 的逐渐升高而增加(RR 间隔的 10%-25%,除了 90 bpm,为 10%),而斜率下降保持在 5%(除了 120 bpm;10%)。
自适应 ECG 脉冲窗口随着 HR 的增加导致额外剂量增加。过渡窗是 14%-34%范围内额外辐射剂量的恒定来源。