Department of Medical Protein Research, VIB, Ghent, Belgium.
Proteomics. 2010 Mar;10(6):1226-9. doi: 10.1002/pmic.200900379.
Manual validation of regulated proteins found in MS-driven quantitative proteome studies is tedious. Here we present Rover (http://genesis.ugent.be/rover), a tool that facilitates this process. Rover accepts quantitative data from different sources such as MASCOT Distiller and MaxQuant and, in an intuitive environment, Rover visualizes these data such that the user can select and validate algorithm-suggested regulated proteins in the frame of the whole experiment and in the context of the protein inference problem.
在 MS 驱动的定量蛋白质组学研究中,对调控蛋白进行手动验证是繁琐的。在这里,我们介绍 Rover(http://genesis.ugent.be/rover),这是一个可以简化这个过程的工具。Rover 可以接受来自不同来源的定量数据,如 Mascot Distiller 和 MaxQuant,并在直观的环境中可视化这些数据,以便用户可以在整个实验的框架内以及蛋白质推断问题的背景下选择和验证算法建议的调控蛋白。