Pautas Eric
Unité gériatrique aiguë, hôpital Charles-Foix (AP-HP), Ivry-sur-Seine, France.
Rev Prat. 2009 Dec 20;59(10):1377-81.
VKA are underused in elderly patients with thrombo-embolic disease, mainly because of their increased risk of bleeding. However, in most cases, evaluation of this risk versus the efficacy in prevention of thrombo-embolic events, should not lead to a therapeutic abstention. The use of VKA in frail elderly patients requires a specific clinical assessment before and during treatment. Moreover, initiation and management of VKA therapy offers some specificities in older patients.
维生素K拮抗剂(VKA)在老年血栓栓塞性疾病患者中未得到充分应用,主要原因是其出血风险增加。然而,在大多数情况下,评估这种风险与预防血栓栓塞事件的疗效相比,不应导致放弃治疗。在体弱的老年患者中使用VKA需要在治疗前和治疗期间进行特定的临床评估。此外,VKA治疗的启动和管理在老年患者中有一些特殊性。