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目前的甘油三酯代谢、病理生理学和治疗概念。

Current concepts in triglyceride metabolism, pathophysiology, and treatment.

机构信息

Department of Medicine, Staten Island University Hospital, Staten Island, NY, USA.

出版信息

Metabolism. 2010 Aug;59(8):1210-20. doi: 10.1016/j.metabol.2009.11.014. Epub 2010 Jan 8.

Abstract

It is becoming more evident that age, gender, and race play a significant role in the metabolic profiles that are seen among individuals in a clinical setting. It is important to understand these variances in metabolic profiles; and with these variances in mind it is now possible to understand why a single diet might not decrease cardiovascular disease risk profiles uniformly for everyone. Much is now understood about triglyceride metabolism and its contribution to energy storage. In this review we will focus on triglycerides; their production, metabolism and influence on daily life, as well as the various methods for the treatment of hypertryglyceridemia and prevention of its sequelae.

摘要

越来越明显的是,年龄、性别和种族在临床环境中个体的代谢特征中起着重要作用。了解代谢特征的这些差异很重要;考虑到这些差异,现在可以理解为什么单一的饮食不可能均匀地降低每个人的心血管疾病风险。现在对甘油三酯代谢及其对能量储存的贡献有了更多的了解。在这篇综述中,我们将重点讨论甘油三酯;它们的产生、代谢及其对日常生活的影响,以及治疗高甘油三酯血症和预防其后果的各种方法。

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