Gonçalo Moniz Research Center, Oswaldo Cruz Foundation, Brazilian Ministry of Health, Rua Waldemar Falcão 121, Salvador, Bahia, 40296, Brazil.
Diabetes Res Clin Pract. 2010 Mar;87(3):407-14. doi: 10.1016/j.diabres.2009.12.014. Epub 2010 Jan 8.
To determine the prevalence of inadequate glycemic control and its correlates in a large multicenter survey of Venezuelan patients with diabetes.
A cross-sectional study in a sample of adult patients with diabetes, attending health centers in Venezuela. Information about diabetes, current medications, complications, and diet were obtained by trained interviewers, using a standardized questionnaire. HbA(1c) was measured by high-performance liquid chromatography in a central laboratory. Patients with HbA(1c) >or=7% were considered to have inadequate glycemic control.
Overall 4075 patients were surveyed, 349(8.6%) with type 1 diabetes (T1D) and 3726(91.4%) with type 2 diabetes(T2D). Subjects' mean age was 58 years, and 65% were female. The prevalence of inadequate glycemic control was 76%. Poor glycemic control was more common in T1D patients (87%) than in those with T2D(75%), p<10(-4). Satisfaction with current diabetes treatment was associated with improved glycemic control among non-insulin-treated patients with T2D, but gender, multi-professional care, and participation in a diabetes education program were not.
Despite clinical evidence supporting tight control of diabetes, few diabetic patients in Venezuela met recommended glycemic control targets. This may contribute to increased rates of diabetic complications. Our findings support the public health message of implementation of early, aggressive management of diabetes.
在委内瑞拉的一项大型多中心糖尿病患者调查中,确定血糖控制不足的患病率及其相关因素。
这是一项在委内瑞拉健康中心就诊的成年糖尿病患者样本中进行的横断面研究。使用标准化问卷,通过受过培训的访谈者收集有关糖尿病、当前药物治疗、并发症和饮食的信息。在一个中心实验室通过高效液相色谱法测量 HbA(1c)。HbA(1c)>或=7%的患者被认为血糖控制不足。
共调查了 4075 名患者,其中 349 名(8.6%)患有 1 型糖尿病(T1D),3726 名(91.4%)患有 2 型糖尿病(T2D)。患者的平均年龄为 58 岁,65%为女性。血糖控制不足的患病率为 76%。T1D 患者(87%)的血糖控制较差,明显高于 T2D 患者(75%),p<10(-4)。在未接受胰岛素治疗的 T2D 患者中,对当前糖尿病治疗的满意度与改善血糖控制相关,但性别、多专业护理和参加糖尿病教育计划则不然。
尽管有临床证据支持严格控制糖尿病,但委内瑞拉的糖尿病患者很少达到推荐的血糖控制目标。这可能导致糖尿病并发症发生率增加。我们的研究结果支持实施早期、积极的糖尿病管理这一公共卫生信息。