São Paulo Federal University, Rua Botucatu, 740, São Paulo, 04023-900, Brazil.
Acta Diabetol. 2010 Jun;47(2):137-45. doi: 10.1007/s00592-009-0138-z. Epub 2009 Aug 5.
Diabetes is a significant public health burden on the basis of its increased incidence, morbidity, and mortality. This study aimed to estimate the prevalence of inadequate glycaemic control and its correlates in a large multicentre survey of Brazilian patients with diabetes. A cross-sectional study was conducted in a consecutive sample of patients aged 18 years or older with either type 1 or type 2 diabetes, attending health centres located in ten large cities in Brazil (response rate = 84%). Information about diabetes, current medications, complications, diet, and satisfaction with treatment were obtained by trained interviewers, using a standardized questionnaire. Glycated haemoglobin (HbA(1c)) was measured by high-performance liquid chromatography in a central laboratory. Patients with HbA(1c) > or = 7 were considered to have inadequate glycaemic control. Overall 6,701 patients were surveyed, 979 (15%) with type 1 and 5,692 (85%) with type 2 diabetes. The prevalence of inadequate glycaemic control was 76%. Poor glycaemic control was more common in patients with type 1 diabetes (90%) than in those with type 2 (73%), P < 0.001. Characteristics significantly associated with improved glycaemic control included: fewer years of diabetes duration, multi professional care, participation in a diabetes health education program, and satisfaction with current diabetes treatment. Despite increased awareness of the benefits of tight glycaemic control, we found that few diabetic patients in Brazil met recommended glycaemic control targets. This may contribute to increased rates of diabetic complications, which may impact health care costs. Our data support the public health message of implementation of early, aggressive management of diabetes.
糖尿病发病率、发病率和死亡率不断上升,给公众健康带来了重大负担。本研究旨在评估巴西大型多中心糖尿病患者中血糖控制不足的患病率及其相关因素。这是一项横断面研究,连续纳入了 18 岁或以上的 1 型或 2 型糖尿病患者,这些患者来自巴西 10 个大城市的医疗中心(应答率为 84%)。通过受过培训的访谈者使用标准化问卷获取有关糖尿病、当前药物治疗、并发症、饮食和治疗满意度的信息。在中央实验室采用高效液相色谱法测定糖化血红蛋白(HbA1c)。HbA1c≥7 的患者被认为血糖控制不足。共有 6701 例患者接受了调查,其中 979 例(15%)为 1 型糖尿病,5692 例(85%)为 2 型糖尿病。血糖控制不足的患病率为 76%。1 型糖尿病患者(90%)的血糖控制不佳比 2 型糖尿病患者(73%)更常见,P<0.001。与改善血糖控制显著相关的特征包括:糖尿病病程较短、多专业护理、参加糖尿病健康教育计划和对当前糖尿病治疗的满意度。尽管人们越来越意识到严格血糖控制的益处,但我们发现巴西的糖尿病患者很少能达到推荐的血糖控制目标。这可能导致糖尿病并发症的发生率增加,从而影响医疗保健成本。我们的数据支持实施早期、积极的糖尿病管理的公共卫生信息。