Gebrie Alemu, Tesfaye Bekele, Sisay Mekonnen
Department of Biomedical Science, School of Medicine, Debre Markos University, Debre Markos, Ethiopia.
Department of Nursing, College of Health Sciences, Debre Markos University, Debre Markos, Ethiopia.
Heliyon. 2020 Dec 3;6(12):e05655. doi: 10.1016/j.heliyon.2020.e05655. eCollection 2020 Dec.
Diabetes mellitus is one of the rapidly growing global health concerns of the twenty-first century ravaging millions of individuals from all across the world. The aim of this study is to evaluate glycemic control status and its associated factors among diabetes patients on follow-up at referral hospitals of Northwest Ethiopia.
A cross-sectional study was conducted among diabetes patients between February and June 2020. Four hundred twenty-three randomly selected adult patients were enrolled. Using standardized questionnaire, sociodemographic, behavioral and clinical data were collected. Lipid profiles, fasting blood sugar, glycated hemoglobin, and anthropometric indicators were determined. Bivariate and multivariate binary logistic regression analysis was performed.
The magnitude of suboptimal glycemic control was 73.5% (95% CI: 69.29%, 77.71%) among diabetic patients. Marital status [AOR (95% CI) 0.45 (0.20, 0.99), p < 0.05], medication non-adherence [poor: AOR (95% CI) 3.55 (1.81, 6.98)], duration with diabetes mellitus [AOR (95% CI) 3.16 (1.89, 5.28), p < 0.05], type of diabetes (type II referent) [AOR (95% CI) 2.53 (1.47,4.37), p < 0.05], and no use of other drugs [AOR (95% CI) 1.76 (1.05,2.96), p < 0.05] were significantly associated with suboptimal glycemic control.
A considerable number of patients with diabetes had suboptimal glycemic control. The suboptimal glycemic control has been contributed by marital status, medication non-adherence, duration with diabetes mellitus, type of diabetes and use of other drugs. These highlights the need for tailored management focusing on the identified associated factors to maintain good glycemic control.
糖尿病是21世纪全球迅速增长的健康问题之一,正在肆虐世界各地数百万人口。本研究的目的是评估埃塞俄比亚西北部转诊医院接受随访的糖尿病患者的血糖控制状况及其相关因素。
于2020年2月至6月对糖尿病患者进行了一项横断面研究。随机选取423例成年患者纳入研究。使用标准化问卷收集社会人口学、行为和临床数据。测定血脂谱、空腹血糖、糖化血红蛋白和人体测量指标。进行了双变量和多变量二元逻辑回归分析。
糖尿病患者血糖控制不佳的比例为73.5%(95%置信区间:69.29%,77.71%)。婚姻状况[AOR(95%置信区间)0.45(0.20,0.99),p<0.05]、药物治疗依从性差[AOR(95%置信区间)3.55(1.81,6.98)]、糖尿病病程[AOR(95%置信区间)3.16(1.89,5.28),p<0.05]、糖尿病类型(以II型为参照)[AOR(95%置信区间)2.53(1.47,4.37),p<0.05]以及未使用其他药物[AOR(95%置信区间)1.76(1.05,2.96),p<0.05]与血糖控制不佳显著相关。
相当数量的糖尿病患者血糖控制不佳。血糖控制不佳是由婚姻状况、药物治疗依从性差、糖尿病病程、糖尿病类型和使用其他药物所致。这些结果凸显了需要针对已确定的相关因素进行个性化管理,以维持良好的血糖控制。