Kurtzberg J, Graham M L
Department of Pediatrics, Duke University Medical Center, Durham, North Carolina.
Pediatr Clin North Am. 1991 Apr;38(2):443-56. doi: 10.1016/s0031-3955(16)38086-5.
The non-Hodgkin's lymphomas are a group of diseases for which substantial progress has been made in understanding tumor biology and effectiveness of treatment during the last decade. These advances may provide insight into the development of neoplasms because of recognized association of lymphomas with viral infections and immunodeficiency. The prognosis for patients with NHL continues to improve. As a result, current studies on treatment of lymphomas in certain favorable stages have concentrated on reducing the intensity of therapy. For patients with advanced disease, further improvements in treatment are still being sought.
非霍奇金淋巴瘤是一组疾病，在过去十年中，人们对其肿瘤生物学和治疗效果的认识取得了重大进展。由于已认识到淋巴瘤与病毒感染和免疫缺陷之间的关联，这些进展可能为肿瘤的发展提供见解。非霍奇金淋巴瘤患者的预后持续改善。因此，目前针对某些有利分期淋巴瘤治疗的研究集中在降低治疗强度上。对于晚期疾病患者，仍在寻求治疗方面的进一步改善。
