Graham M
School of Medicine, Johns Hopkins University, Oncology Center, Johns Hopkins Hospital, Baltimore, MD 21205.
Pediatr Ann. 1988 Mar;17(3):192-3, 197-203. doi: 10.3928/0090-4481-19880301-08.
The non-Hodgkin's lymphomas are a group of diseases for which substantial progress has been made in understanding tumor biology and effectiveness of treatment during the last few years. These advances may provide insight into the development of neoplasms because of recognized association of lymphomas with viral infections and immunodeficiency. The prognosis for patients with non-Hodgkin's lymphomas continues to improve. As a result, current studies on treatment of lymphomas in certain favorable stages have concentrated on reducing the intensity of therapy. For patients with advanced disease, further improvements in treatment are being sought.
非霍奇金淋巴瘤是一组疾病，在过去几年中，我们对其肿瘤生物学和治疗效果的理解取得了重大进展。由于已认识到淋巴瘤与病毒感染和免疫缺陷之间的关联，这些进展可能为肿瘤的发展提供见解。非霍奇金淋巴瘤患者的预后持续改善。因此，目前针对某些有利阶段淋巴瘤治疗的研究集中在降低治疗强度上。对于晚期疾病患者，正在寻求进一步的治疗改进。
