Sarma Deba P, Stevens Todd
Department of Pathology, Creighton University Medical Center, Omaha, NE 68131, USA.
Cases J. 2009 Nov 30;2:9118. doi: 10.1186/1757-1626-2-9118.
Differential diagnosis for a nodule in the nipple or subareolar area of woman includes both primary neoplasms of breast as well as those from skin and adnexae.
A 32-year-old woman presented with a painless 0.5 cm subareolar nodule of her left nipple that she had noticed for several months, with no associated nipple discharge. A biopsy revealed an infiltrating adnexal neoplasm with features similar to those seen in syringomas commonly occurring in locations such as upper face and pubis. The infiltrating syringomatous adenoma of the nipple occurs almost exclusively in women of all ages and is cured by simple excision. Microscopic appearance of such a rare benign infiltrating neoplasm of eccrine duct origin occurring in woman's breast should not be misinterpreted as more common infiltrating primary breast carcinoma.
Infiltrating eccrine syringomatous adenoma should be included in the differential diagnosis of a nipple or subareolar nodule occurring in woman.
女性乳头或乳晕下区域结节的鉴别诊断包括乳腺原发性肿瘤以及皮肤和附属器来源的肿瘤。
一名32岁女性，左侧乳头乳晕下有一个0.5厘米大小的无痛性结节，她已注意到几个月，无乳头溢液。活检显示为浸润性附属器肿瘤，其特征与常见于上睑和耻骨等部位的汗管瘤相似。乳头浸润性汗管瘤样腺瘤几乎仅发生于各年龄段女性，通过单纯切除可治愈。这种罕见的起源于小汗腺导管的女性乳腺良性浸润性肿瘤的显微镜下表现不应被误诊为更常见的浸润性原发性乳腺癌。
浸润性小汗腺汗管瘤样腺瘤应纳入女性乳头或乳晕下结节的鉴别诊断。
