Ishikawa Shoichi, Sako Hirotaka, Masuda Koji, Tanaka Tomoko, Akioka Kiyokazu, Yamamoto Yoshihiro, Hosokawa Yohei, Manabe Toshiaki
Department of Surgery, Omihachiman Community Medical Center, 1379 Tsuchida-cho, Omihachiman City, Shiga, 523-0082, Japan.
Department of Pathology and Laboratory Medicine, Omihachiman Community Medical Center, 1379 Tsuchida-cho, Omihachiman City, Shiga, 523-0082, Japan.
J Med Case Rep. 2015 Nov 13;9:256. doi: 10.1186/s13256-015-0739-9.
Syringomatous adenoma of the nipple is a very rare benign tumor. To the best of our knowledge, there are no reports of a syringomatous adenoma of the nipple metastasizing, although these tumors are known to infiltrate locally and to recur if not totally resected.
Our patient was a 41-year-old Japanese woman who complained of stiffness of her right nipple with abnormal discharge. Local resection of the tumor was performed. The pathological diagnosis was syringomatous adenoma of the nipple, and the resection margin was found to be positive. Accordingly, additional resection was recommended, but our patient did not allow another operation. After 1.5 years of careful follow-up, no local recurrence or distant metastasis has been observed.
The optimal initial management of syringomatous adenoma of the nipple demands complete resection with histologically negative margins. However, from a cosmetic viewpoint, nipple-sparing resection could represent an alternative option for the treatment of syringomatous adenoma of the nipple.
乳头汗腺腺瘤是一种非常罕见的良性肿瘤。据我们所知，尚无乳头汗腺腺瘤发生转移的报道，尽管已知这些肿瘤会局部浸润，若未完全切除则会复发。
我们的患者是一名41岁的日本女性，主诉右乳头僵硬伴异常溢液。对肿瘤进行了局部切除。病理诊断为乳头汗腺腺瘤，且切除边缘呈阳性。因此，建议进行再次切除，但我们的患者不允许再次手术。经过1.5年的密切随访，未观察到局部复发或远处转移。
乳头汗腺腺瘤的最佳初始治疗需要进行组织学切缘阴性的完整切除。然而，从美容角度来看，保留乳头的切除术可能是乳头汗腺腺瘤治疗的另一种选择。
