基于肽的活性探针 (ABPs) 用于特定于目标的蛋白质酪氨酸磷酸酶 (PTPs) 的分析。
Peptide-based activity-based probes (ABPs) for target-specific profiling of protein tyrosine phosphatases (PTPs).
机构信息
Department of Chemistry, National University of Singapore, 3 Science Drive 3, Singapore 117543.
出版信息
Chem Commun (Camb). 2010 Jan 28;46(4):589-91. doi: 10.1039/b919744c. Epub 2009 Nov 17.
DOI:10.1039/b919744c
PMID:20062871
Abstract
Synthesis of a novel unnatural amino acid (2-FMPT) for the solid-phase synthesis of peptide-based probes suitable for target-specific activity-based profiling of protein tyrosine phosphatases from crude proteomes is reported.
摘要
报道了一种新型非天然氨基酸（2-FMPT）的合成，用于基于肽的探针的固相合成，该探针适用于从粗蛋白质组中针对蛋白质酪氨酸磷酸酶的靶标特异性活性的基于探针的蛋白质组学分析。
Zotero 插件