基于自组装包合作用的可降解中空球

Degradable hollow spheres based on self-assembly inclusion.

机构信息

State Key Laboratory of Polymer Materials Engineering (Sichuan University), Polymer Research Institute of Sichuan University, Chengdu 610065, China.

出版信息

Chem Commun (Camb). 2010 Jan 28;46(4):643-5. doi: 10.1039/b916224k. Epub 2009 Nov 20.

DOI:10.1039/b916224k

PMID:20062889

Abstract

Degradable hollow nanospheres are prepared by self-assembly of rod-coil Alg-g-PEG/alpha-CD (Alginate-g-Poly(ethylene glycol)/alpha-Cyclodextrin) complexes in water, in which the rod-like segments were formed by inclusion between alpha-CDs and grafted PEG chains and the coil-like segments were protonated alginate backbones.

摘要

可降解中空纳米球通过在水中自组装棒状-线团状 Alg-g-PEG/α-CD（藻酸盐-g-聚乙二醇/α-环糊精）复合物制备而成，其中棒状段由α-CD 与接枝的 PEG 链之间的包合形成，线团状段为质子化的藻酸盐主链。