University of Birmingham Centre for Cardiovascular Sciences, City Hospital, Birmingham, B18 7QH, United Kingdom.
Thromb Haemost. 2010 Jan;103(1):13-28. doi: 10.1160/TH09-08-0580. Epub 2009 Sep 30.
There remains uncertainty over optimal antithrombotic management strategy for patients with atrial fibrillation (AF) presenting with an acute coronary syndrome and/or undergoing percutaneous coronary intervention/stenting. Clinicians need to balance the risk of stroke and thromboembolism against the risk of recurrent cardiac ischaemia and/or stent thrombosis, and the risk of bleeding. This consensus document comprehensively reviews the published evidence and presents a consensus statement on a 'best practice' antithrombotic therapy guideline for the management of antithrombotic therapy in such AF patients.
对于伴有急性冠状动脉综合征和/或接受经皮冠状动脉介入治疗/支架置入术的心房颤动(AF)患者,其最佳抗栓管理策略仍存在不确定性。临床医生需要权衡中风和血栓栓塞风险与复发性心肌缺血和/或支架血栓形成风险以及出血风险。本共识文件全面审查了已发表的证据,并就 AF 患者抗栓治疗管理的“最佳实践”抗栓治疗指南提出了共识声明。