Servicio de Pediatría, Hospital Clínico San Cecilio, c/Málaga 1, 18170 Alfacar, Granada, Spain.
Eur J Clin Microbiol Infect Dis. 2010 Mar;29(3):333-4. doi: 10.1007/s10096-009-0849-7.
We analysed the asymptomatic carrier state of Neisseria meningitidis in a sample of 339 children. We obtained data for the children's weight and height, in order to calculate the body mass index (BMI). The cutoff points defined by Cole were employed in determining the BMI, and the population was divided into three groups: normal, overweight and obese. Twenty carriers of N. meningitidis were identified. There was found to be a statistically significant trend to increased risk of being a carrier with increased BMI (z=2.03; P=0.04); after adjusting for age using the Mantel-Haenszel weighting method, this relationship was strengthened (z=2.38; P=0.01). Paediatric patients with increased BMI in the range of obesity present a three times greater risk of being carriers of N. meningitidis than non-obese patients, with a trend for this risk to increase with higher BMI.
我们分析了 339 名儿童中脑膜炎奈瑟菌的无症状携带者状态。我们获得了儿童体重和身高的数据，以便计算体重指数（BMI）。采用科尔定义的切点来确定 BMI，并将人群分为三组：正常、超重和肥胖。确定了 20 名脑膜炎奈瑟菌携带者。结果发现，随着 BMI 的增加，携带者的风险呈显著上升趋势（z=2.03；P=0.04）；使用 Mantel-Haenszel 加权法调整年龄后，这种关系得到了加强（z=2.38；P=0.01）。肥胖范围内 BMI 增加的儿科患者携带脑膜炎奈瑟菌的风险是不肥胖患者的三倍，并且随着 BMI 的增加，这种风险呈上升趋势。
