Department of Internal Medicine, College of Medicine, Dong-A University, Pusan, Korea.
Rheumatol Int. 2012 Apr;32(4):1065-8. doi: 10.1007/s00296-009-1354-0. Epub 2010 Jan 10.
Kaposi sarcoma (KS) is a vascular neoplasm mainly affecting the skin of the limbs that has previously been associated with rheumatoid arthritis (RA). When compared with the RA patients treated with corticosteroids and immunosuppressive drugs, the reported number of KS in RA patients was very rare. Although the exact mechanisms of developing KS in RA patients are unclear, some drugs which include corticosteroid have been suggested as an etiological factor in previous case reports of RA and KS. We report, here in, another case of KS associated with the initiation of leflunomide in a patient with RA.
卡波西肉瘤（KS）是一种主要影响四肢皮肤的血管肿瘤，以前与类风湿关节炎（RA）有关。与接受皮质类固醇和免疫抑制剂治疗的 RA 患者相比，报告的 RA 患者 KS 病例非常罕见。虽然 RA 患者发生 KS 的确切机制尚不清楚，但一些药物，包括皮质类固醇，在以前的 RA 和 KS 病例报告中被认为是一个病因因素。我们在此报告另一个 RA 患者在开始使用来氟米特后出现 KS 的病例。
