Institute of Music Physiology and Musicians' Medicine, University of Music and Drama, Hanover, Germany.
Mov Disord. 2010 Feb 15;25(3):389-94. doi: 10.1002/mds.22938.
Musician's dystonia (MD) is a task-specific movement disorder with a loss of voluntary motor control in highly trained movements. Defective inhibition on different levels of the central nervous system is involved in its pathophysiology. Cathodal transcranial direct current stimulation (ctDCS) diminishes excitability of the motor cortex and improves performance in overlearned tasks in healthy subjects. The aim of this study was to investigate whether ctDCS improves fine motor control in MD. Professional guitarists (n = 10) with MD played exercises before, directly after ctDCS, and 60 min after ctDCS. ctDCS (2 mA, 20 min) was applied on the primary motor cortex contralateral to the affected hand. Guitar exercises were video-documented and symptoms were evaluated by three independent experts. No beneficial effect of ctDCS on fine motor control was found for the entire group. However, motor control of one guitarist improved after stimulation. This patient suffered from arm dystonia, whereas the other guitarists suffered from hand dystonia.
音乐家手颤（MD）是一种特定于任务的运动障碍，表现为高度训练的运动中失去自主运动控制。其病理生理学涉及中枢神经系统不同水平的抑制缺陷。经颅直流电刺激（ctDCS）降低运动皮层的兴奋性，并改善健康受试者对过度学习任务的表现。本研究旨在探讨 ctDCS 是否能改善 MD 患者的精细运动控制。患有 MD 的专业吉他手（n = 10）在接受 ctDCS 治疗前、治疗后即刻和治疗后 60 分钟进行练习。ctDCS（2 mA，20 分钟）施加于患手对侧的初级运动皮层。吉他练习通过视频记录，由三位独立专家进行症状评估。整个组中没有发现 ctDCS 对精细运动控制有有益的影响。然而，一位吉他手在刺激后其运动控制有所改善。这名患者患有手臂手颤，而其他吉他手则患有手部手颤。
