Department of Pharmacy, Lanzhou General Hospital of PLA, Lanzhou 730050, PR China.
J Ethnopharmacol. 2010 Mar 24;128(2):279-313. doi: 10.1016/j.jep.2010.01.006. Epub 2010 Jan 11.
Scutellaria (HUANG QIN) (Lamiaceae), which includes about 350 species commonly known as skullcaps, is widespread in Europe, the United States and East Asia. Some species are taken to clear away the heat-evil and expel superficial evils in traditional Chinese medicine (TCM). The present paper reviews the ethnopharmacology, the biological activities and the correlated chemical compounds of Scutellaria species. More than 295 compounds have been isolated, among them flavonoids and diterpenes. Studies show that Scutellaria and its active principles possess wide pharmacological actions, such as antitumor, anti-angiogenesis, hepatoprotective, antioxidant, anticonvulsant, antibacterial and antiviral activities. Currently, effective monomeric compounds or active parts have been screened for pharmacological activity from Scutellaria in vivo and in vitro. Increasing data supports application and exploitation for new drug development.
黄芩（唇形科），约有 350 种，通常被称为黄芩，广泛分布于欧洲、美国和东亚。一些种类被用于清除中医中的热邪和外邪。本文综述了黄芩属植物的民族药理学、生物活性和相关化学化合物。已经分离出超过 295 种化合物，其中包括黄酮类化合物和二萜类化合物。研究表明，黄芩及其活性成分具有广泛的药理作用，如抗肿瘤、抗血管生成、保肝、抗氧化、抗惊厥、抗菌和抗病毒活性。目前，已经从黄芩中筛选出具有体内和体外药理活性的有效单体化合物或活性部位。越来越多的数据支持将其应用于新药开发。
