Ngueyem T A, Brusotti G, Caccialanza G, Finzi P Vita
Department of Pharmaceutical Chemistry, University of Pavia, Pavia, Italy.
J Ethnopharmacol. 2009 Jul 30;124(3):339-49. doi: 10.1016/j.jep.2009.05.019. Epub 2009 May 27.
Approximately 60 species of Bridelia, (Phyllanthaceae) are found throughout tropical and subtropical regions of the world, mainly in Africa and Asia. Several Bridelia species are used in popular medicines as antiamebic, antianemic, antibacterial, anticonvulsant, anti-diabetic, antidiarrhoeal, antihelmintic, anti-inflammatory, antimalarial, antinociceptive, antiviral, hypoglycemic and for abdominal pain, cardiovascular, gynecological and sexual diseases. The present paper reviews the traditional usage, the biological activities and the correlated chemical compounds of Bridelia species with emphasis on the validation of the ethnopharmacological uses. The findings in some Bridelia species of, for example, gallocatechin-(4'-O-7)-epigallocatechin (1), quercetin (2), myricetin glycosides (5-6), bridelone (11), bridelonine (12), isoflavone may justify the uses of these species against pains in African and Asian traditional medicines.
土蜜树属（叶下珠科）约有60个物种，分布于世界热带和亚热带地区，主要在非洲和亚洲。几种土蜜树属植物在传统药物中用于治疗阿米巴病、贫血、抗菌、抗惊厥、抗糖尿病、止泻、驱虫、抗炎、抗疟疾、抗伤害感受、抗病毒、降血糖以及治疗腹痛、心血管疾病、妇科疾病和性疾病。本文综述了土蜜树属植物的传统用途、生物活性及相关化合物，重点是对其民族药理学用途的验证。在一些土蜜树属植物中发现的表儿茶素-（4'-O-7）-表没食子儿茶素（1）、槲皮素（2）、杨梅素苷（5 - 6）、土蜜树酮（11）、土蜜树宁（12）、异黄酮等成分，可能解释了这些植物在非洲和亚洲传统医学中用于止痛的原因。
